In a nutshell This study wanted to find out what factors put young people with type 1 diabetes at risk of developing impaired blood flow or heart issues. The study found that poor control of blood sugars and traditional risk factors for heart disease, such as high blood pressure and obesity, were associated with an increased risk of blood flow issues in...
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Triple therapy vs double therapy in uncontrolled type 2 diabetes
In a nutshell This article investigated the safety and effectiveness of triple therapy with low dose dapagliflozin (Farxiga) plus saxagliptin (Onglyza) added to metformin (Glucophage) in uncontrolled type 2 diabetes (T2D). The authors concluded that triple therapy significantly improved blood glucose control in these patients. Some background T2D...
Read MoreRisk factors for atrial fibrillation in people with type 1 diabetes
In a nutshell This article investigated the factors associated with an increased risk of developing atrial fibrillation (AF; irregular heart beat) in people with type 1 diabetes (T1D). The authors concluded that other heart conditions, kidney disease, and older age increase the risk of developing AF in these patients. Some background AF is an...
Read MoreSearching for patients with type 1 diabetes to test a closed-loop strategy
In a nutshell This trial is examining the effectiveness and safety of single-hormone closed-loop (SHCL) compared with sensor-augmented pump therapy (SAPT) in controlling glucose levels in patients with type 1 diabetes (T1D). The main outcome to be measured will be the percentage of time that glucose levels are between 3.9 and 10...
Read MoreIs non-Hodgkin’s lymphoma associated with type 1 and type 2 diabetes?
In a nutshell This article compared the association between non-Hodgkin’s lymphoma (NHL) with type 1 (T1D) and type 2 diabetes (T2D). The authors concluded that there was an increase in the risk of NHL in both T1D and T2D. Some background NHL is a cancer that starts in white blood cells called lymphocytes, which are part of the...
Read MorePreserving beta cell function in patients with latent autoimmune diabetes in adults
In a nutshell This article compared beta cell function (BCF) preservation with insulin vs sitagliptin (Januvia) in the management of latent autoimmune diabetes in adults (LADA). The authors concluded that BCF preservation was similar with insulin and sitagliptin in patients with LADA. Some background In LADA,...
Read MoreEfficacy and safety of basal-bolus insulin vs glp-1 receptor agonist plus basal insulin in patients with uncontrolled type 2 diabetes
In a nutshell This article compared the safety and effectiveness of insulin detemir (Levemir) plus liraglutide (Victoza) vs insulin detemir plus insulin aspart (Novolog) in the management of type 2 diabetes (T2D). The authors concluded that detemir plus liraglutide is a safe and more...
Read MoreHow common is undiagnosed coronary artery disease in adult patients with long term type 1 diabetes?
In a nutshell This article investigated the frequency of undiagnosed coronary artery disease (CAD) in patients with long-term type 1 diabetes (T1D). The authors concluded that UCAD was very common and that high cholesterol and HbA1c (a measure of blood glucose control over the past 3 months) were associated with CAD. Some background...
Read MoreHow often should self-monitoring of blood glucose be done in patients with type 2 diabetes?
In a nutshell This article investigated the impact of self-monitoring of blood glucose (SMBG) frequencies on glucose control (GC) in patients with type 2 diabetes (T2D) who are not on insulin. The authors concluded that frequent SMBG (8-14 times/week) is effective for these patients. Some background T2D is a disorder where the body can no longer...
Read MoreInduction of labor vs expectant management for gestational diabetes
In a nutshell This article investigated whether the induction of labor (IOL) in mothers with gestational diabetes (GDM) at term decreases cesarean section (CS) rate and the rate of adverse neonatal outcomes compared with expectant management (EM). The authors concluded that IOL in GDM mothers at term does not reduce CS rate and is associated with an...
Read MoreLaser treatment combined with growth factor injection for diabetic macular edema
In a nutshell This article investigated the effect of minimally invasive laser treatment combined with injection of anti-vascular endothelial growth factor (VEGF) for diabetic macular edema (DME) in patients with diabetes. The authors concluded that this combination therapy improved visual acuity (VA; how clear you can see) and alleviated...
Read MoreEffect of alogliptin on blood pressure in hypertensive patients with type 2 diabetes
In a nutshell This article investigated the effect of alogliptin (Nesina) on blood pressure (BP) in patients with hypertension (HTN; high blood pressure) and type 2 diabetes (T2D). The authors concluded that alogliptin was associated with improved blood sugar control, BP and arterial stiffness in these patients. Some...
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