In a nutshell This study investigated how common symptoms of anxiety and depression are amongst patients with diabetes mellitus. This study concluded that 1 in 10 patients had symptoms of both anxiety and depression. Some background Depression is nearly twice as common in adults with diabetes compared to the general population. Approximately 1 in 5...
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Can succinate levels in the blood indicate remission of Type 2 diabetes?
In a nutshell This study examined if the levels of succinate in the blood could indicate remission of Type 2 diabetes (T2D) in patients that had bariatric surgery. The authors found that succinate levels were lower in patients who achieved remission of T2D after surgery. Some background One of the main goals of treatment for T2D is to lower...
Read MoreBexagliflozin for patients with type 2 diabetes
In a nutshell This study wanted to evaluate the safety and effectiveness of bexagliflozin in patients with type 2 diabetes (T2D). The study found that this treatment was safe and significantly improved the outcomes of these patients. Some background Bexagliflozin is a new medication for treating T2D. It is part of a larger class of...
Read MoreCan metformin help reduce the risk of developing neurodegenerative disease in elderly patients with T2D?
In a nutshell This study examined if metformin (Glucophage) helped reduce the risk of neurodegenerative disease in elderly patients with Type 2 diabetes (T2D). The authors found that patients taking metformin for more than two years had a lower risk of brain degeneration diseases compared to patients not taking metformin. Some...
Read MoreCan linagliptin improve glucose control in older people with type 2 diabetes?
In a nutshell This study examined if linagliptin (Tradjenta) was safer and more effective in older patients with Type 2 diabetes compared to a placebo. This study concluded that linagliptin helped improve glucose control for these patients without causing additional side effects. Some background About 90% of diabetes cases are of Type 2 diabetes...
Read MoreDo low-glycemic diets benefit patients with diabetes?
In a nutshell This study examined if low-glycemic index (GI) diets can help improve symptoms of diabetes and pre-diabetes. This study concluded that low-GI diets might help reduce blood sugar levels and body weight in these patients. Some background Patients with pre-diabetes, T1D, or T2D have difficulty controlling their blood glucose levels. The...
Read MoreLooking for patients with type 2 diabetes and high cholesterol to test a cholesterol-reducing drug combination
In a nutshell This trial is examining how effective the drug bempedoic acid is when used with ezetimibe (Zetia) to reduce cholesterol in patients with type 2 diabetes (T2D). The main outcome will be the measurement of patient’s cholesterol as well as heart disease risk, diabetes severity and drug side effects. This study is recruiting in...
Read MoreIncreasing doses of sotagliflozin in patients with type 1 diabetes
In a nutshell This study wanted to find out the effect of the medication sotagliflozin (Zynquista) at different doses on the blood sugar levels and weight of people with type 1 diabetes. The study found that at higher doses, sotagliflozin decreased the blood sugar levels and weight of these patients. Some background Sotagliflozin is a new medication...
Read MoreAssessment of new predictors of kidney disease in patients with type 2 diabetes
In a nutshell This study evaluated the accuracy of four new predictors of kidney damage and disease are compared to the standard test for patients with Type 2 diabetes (T2D). The authors found that these new predictors were as accurate as the standard test at detecting kidney disease. Some background Many patients with Type 2 diabetes (T2D)...
Read MoreDoes the addition of a statin drug to standard therapy reduce kidney disease in patients with diabetes?
In a nutshell This study examined if adding atorvastatin (Lipitor) to irbesartan (Avapro) helped reduce early kidney disease in patients with diabetes. The authors found that adding atorvastatin reduced a number of symptoms of kidney disease for these patients. Some background Patients with diabetes mellitus often experience complications,...
Read MoreContinuous glucose monitoring targets in pregnant women with type 1 diabetes
In a nutshell This study reviewed the use of continuous glucose monitoring (CGM) in pregnancy for women with type 1 diabetes (T1D). Some background Continuous glucose monitoring (CGM) automatically tracks blood glucose levels throughout the day and night. A CGM works through a tiny sensor inserted under the skin. The sensor tests...
Read MoreSGLT-2 inhibitors and lower limb amputation risk in people with type 2 diabetes
In a nutshell This study wanted to find out if treating type 2 diabetes with SGLT-2 inhibitors increases the risk of disease in blood vessels or the risk of amputation of the feet. The study found that treating type 2 diabetes with certain SGLT-2 inhibitors such as canagliflozin (Invokana) may be associated with an increased risk of disease in the...
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