In a nutshell This study investigated whether sodium-glucose cotransporter 2 (SGLT2) inhibitors could help slow down the progression of kidney disease in patients with type 2 diabetes (T2D). This study concluded that SGLT2 inhibitors slowed down kidney function decline compared to other anti-diabetes medications. Some background T2D often leads to...
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In a nutshell This study evaluated the safety and effectiveness of a combination treatment between sodium-glucose cotransporter 2 (SGLT) inhibitors and glucagon-like peptide 1 (GLP1) receptor agonists for patients with Type 2 diabetes (T2D). This study concluded that combination treatment improved blood glucose control and reduced weight loss for...
Read MoreIn a nutshell This study wanted to find out if people with type 1 diabetes who use insulin pumps have fewer changes in their blood glucose control than those who use multiple daily injections. The study found that the patients who used insulin pumps had fewer changes in blood glucose control than those on multiple daily...
Read MoreIn a nutshell This study looked at the effect of dapagliflozin (Farxiga) on kidney disease in patients with type 2 diabetes. It found patients treated with dapagliflozin were significantly less likely to have a decline in kidney function. Some background In type 2 diabetes (T2D), the body no longer regulates blood sugar well. If blood sugar is not...
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In a nutshell This study investigated whether thiazolidinediones (TZDs) can help lower the risk of Parkinson’s disease (PD) in patients with type 2 diabetes (T2D). The authors concluded that TZDs were associated with a lower risk of PD in these patients. Some background Although anti-diabetes medications can help lower blood sugar...
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In a nutshell This study evaluated the safety and effectiveness of switching to insulin degludec (Tresiba) in patients with diabetes mellitus. This study concluded that patients had better blood glucose control and a lower risk of low blood sugar after switching. Some background Insulin therapy is the typical first-line treatment for patients...
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In a nutshell This study is looking for patients with diabetes taking insulin to test a mobile app that helps patients understand how blood glucose levels change. The main outcome that will be measured is the average blood glucose level at the beginning versus the end of the study. This study is recruiting in Boston, MA, the US. The details...
Read MoreIn a nutshell This trial is testing the effectiveness of once-daily vs thrice-daily oral insulin in patients with type 1 diabetes (T1D). The main outcome is the amount of injected insulin used, and the second outcome is the amount of time blood glucose levels are within specific ranges. This study is being conducted in Orange County, California,...
Read MoreIn a nutshell This study is examining the effectiveness of insulin inhaler Afrezza at mealtimes for patients with type 2 diabetes (T2D). The main outcome of the study will be the time patients’ blood glucose readings are in the ideal range. This study is recruiting in San Antonio, TX, US. The details T2D is a disease where a...
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In a nutshell This study examined the frequency of sodium-glucose cotransporter 2 (SGLT2) inhibitor use in type 1 diabetes (T1D) and the resulting rates of diabetic ketoacidosis (DKA). The study concluded that while the proportion of SGLT2 use in T1D is small, there is a significant associated risk of DKA. Some background There are two...
Read MoreIn a nutshell This study compared the safety and effectiveness of semaglutide (Ozempic) and canagliflozin (Invokana) for patients with uncontrolled type 2 diabetes (T2D). The authors found that semaglutide more effectively reduced blood glucose levels and body weight than canagliflozin. Some background Often, patients with T2D are given...
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In a nutshell This study examined the effect of SGLT2 inhibitors on symptoms of kidney disease in patients with Type 2 diabetes (T2D). The authors found that these agents helped lower the chance of developing kidney disease in these patients. Some background In patients with diabetes, high blood glucose levels can lead to other health...
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