In a nutshell This study looked at the benefit of injecting a steroid pellet into the eye during cataract surgery in patients with diabetic eye disease. They found that steroid injections reduced the risk of complications in patients with diabetic eye disease. Some background Patients with diabetes often suffer from fluid in the...
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In a nutshell This study looked at using a closed-loop system, which connects glucose tests automatically to an insulin pump, for children with type 1 diabetes (T1D). It found that a closed-loop system improved glucose control in these patients. Some background T1D is a condition in which the pancreas is unable to create the hormone insulin,...
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In a nutshell This study looked at the treatment of type 2 diabetes with either daily or weekly insulin injections. They found that weekly insulin was as safe and effective as daily injections. Some background Glycated hemoglobin (Hba1c) is a measurement of how well a person’s blood sugars are controlled over a 3 month period. This is...
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In a nutshell This study looked at the risk of dementia in patients with type 2 diabetes (T2D) taking metformin (Glucophage) and those not taking this drug. They found that patients taking metformin were at a lower risk to develop dementia. Some background Dementia is the loss of mental capacities such as memory, reasoning,...
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In a nutshell This trial is being carried out to examine the effectiveness of LY3016859 for diabetic neuropathic pain (DNP; pain caused by damage to the nerves). The main outcome to be measured is a change in pain intensity. This study is being carried out in Puerto Rico and the United States. The details Uncontrolled diabetes can lead...
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In a nutshell This study looked at the effect of vitamin D supplements on diabetic neuropathy (DN; nerve damage). They found that taking high-dose vitamin D for 6 months reduced the pain and disability associated with DN. Some background Diabetic neuropathy (DN) refers to nerve damage experienced by diabetic patients. It leads to pain and...
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In a nutshell This study investigated the risk of foot amputation (removal of the foot or part of it) in patients with diabetic foot ulcers to see what factors increase this risk. They found that being male, smoking, and having a history of previous foot ulcers all increased the risk of amputation. Some background Foot ulcers are a...
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In a nutshell This study looked at the risk of heart disease, stroke, and other complications in diabetic patients with low thyroid function (hypothyroidism; HT). They found that diabetic patients with HT were not at increased risk of major heart disease or stroke. However, these patients were more likely to develop diabetic eye disease and...
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In a nutshell This trial is being carried out to assess the effectiveness of a port delivery system (PDS) loaded with ranibizumab (Lucentis) in order to prevent further progression of diabetic retinopathy (DR; diabetic eye disease). The main outcome of this trial is to assess the improvement in DR following implantation with a PDS. This trial...
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In a nutshell This study examined the effectiveness and risks of polyethylene glycol loxenatide (PEX168) as an add-on to metformin (Glucophage) therapy in patients with type 2 diabetes (T2D). It found that PEX168 is safe and works effectively in improving the blood sugar levels in these patients. Some background T2D is a...
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In a nutshell This study compared real-time continuous glucose monitoring (CGM) to flash CGM for patients with type 1 diabetes (T1D). It found that real-time CGM led to better glucose control and less hypoglycemia, both during daily activity and exercise. Some background Patients with T1D are unable to create the hormone insulin to regulate blood...
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In a nutshell This study examined the role of statin (cholesterol-lowering) therapy in lowering the risk of diabetic eye disease and sight-threatening complications of diabetes. They found that patients taking a statins were less likely to suffer from advanced diabetic eye disease than those not taking a statin. Some background...
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