In a nutshell This study looked at the treatment of severe diabetic macular edema (DME). It compared eyes treated with surgery to eyes treated with injections. It showed that surgical treatment leads to a better resolution of DME compared to injections. Some background Diabetic eye disease affects the retina, which is the layer of...
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In a nutshell This study looked at the benefits and risks of gastric bypass surgery (GBS) in patients with type 1 diabetes (T1D) and obesity. They found that GBS was associated with reduced risk of heart disease, stroke and heart failure in these patients. However it was also associated with increased episodes of high blood sugar and abuse...
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In a nutshell This report gave an overview of oral medications to help in managing obesity. Some background Obesity is a worldwide health issue. People with obesity are at increased risk of a variety of health conditions, including heart disease, type 2 diabetes (T2D), and several types of cancer. Obesity is complex, and there are multiple...
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In a nutshell This study examined the risk of major heart complications in patients taking a type of diabetic medication called DPP4-inhibitors. They found that patients taking DPP4-inhibitors were less likely to develop major heart disease than patients taking sulfonylureas. Some background Patients with type 2 diabetes (T2D) are at risk...
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In a nutshell This trial is looking to recruit patients with diabetic macular edema (DME) to trial a new gene therapy, ADVM-022. This trial is aiming to measure the time it takes for DME to worsen. This trial is being carried out in Puerto Rico and the United States. The details DME affects up to 10% of people with diabetes and is caused by fluid...
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In a nutshell This controlled trial looked at adding exenatide (Byetta) to intensive insulin treatment for patients with type 2 diabetes (T2D) who still had high blood sugar. It found that the exenatide improved blood sugar control and reduced body weight in these patients. Some background T2D is a metabolic condition in which the body does not...
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In a nutshell This study compared treatments for fatty liver disease in patients with type 2 diabetes (T2D). They found that liraglutide (Victoza) reduced liver fat significantly, improved liver function, and led to weight loss and better blood sugar control. Some background Half of the patients with T2D can have liver disease...
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In a nutshell This study looked at how pre-conception care (PCC) relates to outcomes for women with diabetes and their infants. It found that women who received PCC had improved blood sugar control during pregnancy and fewer birth defects and pre-term births. Some background Diabetes during pregnancy increases the risks to both the woman and the...
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In a nutshell This study looked at whether low levels of vitamin D increased complications for patients with type 2 diabetes (T2D). It found that foot ulcers were more common for patients who had low vitamin D (LVD). Some background T2D is a condition in which the body cannot control levels of glucose (sugar) in the blood. Over time, high blood...
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In a nutshell This study compared people with type 2 diabetes (T2D) who had weight loss surgery to those who lost an equal amount of weight through diet. It found that both methods of weight loss led to improvements in blood sugar, insulin sensitivity, and metabolism. Some background T2D is a condition in which the body cannot control levels of...
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In a nutshell This study looked at the use of mirogabalin (Tarlige) to treat diabetic peripheral neuropathic pain (DPNP). It found that mirogabalin was safe and effective at reducing pain in DPNP. Some background Diabetic peripheral neuropathic pain (DPNP) is a pain experienced by some diabetic patients due to nerve damage. This pain,...
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In a nutshell This study looked at the effect of vitamin D levels in reducing the risk of full-blown diabetes in people with prediabetes. They found that having high levels of vitamin D reduced the risk of developing diabetes. Some background Prediabetes means a higher than normal blood glucose (sugar) level. However, not high enough...
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