In a nutshell This study looked at the effect of treatment with polyethylene glycol loxenatide (PEX168) alone in patients with poorly controlled type 2 diabetes (T2D). They found that PEX168 significantly improved blood glucose control in these patients. Some background Blood glucose is controlled by many hormones. The most...
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In a nutshell This study looked at the use of sotagliflozin (Zynquista) in patients with poorly controlled type 2 diabetes (T2D) and chronic kidney disease (CKD). It found that patients taking sotagliflozin was associated with a lower risk of heart attack, stroke, or death. Some background Patients with T2D and CKD are...
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In a nutshell This study compared hybrid closed-loop (HCL) insulin delivery to an insulin pump or daily injections for adults with type 1 diabetes (T1D). It found that an HCL system led to better glucose control and a more positive experience of managing diabetes. Some background For many patients with T1D, managing blood glucose (sugar) levels is a...
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In a nutshell This study looked at the safety and benefits of starting sotagliflozin (Zynquista) in patients with type 2 diabetes (T2D) who were recently hospitalized for heart failure. They found that patients started on sotagliflozin within 2 days of discharge from the hospital had a lower risk of serious complications including...
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In a nutshell This study looked at the treatment of poorly-controlled type 2 diabetics. They found that a combination of exenatide and dapagliflozin was more effective at lowering blood glucose (sugar) than either treatment alone. Some background There are many types of treatment for type 2 diabetes (T2D). Metformin (Glucophage) is commonly...
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In a nutshell This study compared the use of steroid eye injections with other treatments for diabetic macular edema (DME). They found that steroid injections may improve vision slightly compared to placebo, but are possibly less effective than other types of injection. Steroid injections also increase the risk of cataracts and increased...
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In a nutshell This study compared the safety of two medications, linagliptin (Trajenta) and glimepiride (Amaryl). It found that the medications had the same risk of heart attack, stroke, or heart-related death, while linagliptin was associated with a lower risk of hypoglycemia (dangerously low blood glucose level). Some background There...
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In a nutshell This study looked at the safety and effectiveness of adding dapagliflozin (Forxiga) in poorly controlled type 1 diabetes (T1D). It found that patients treated with dapagliflozin had better blood glucose (sugar) control and more weight loss after 12 months than patients treated with placebo. Some background Dapagliflozin belongs...
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In a nutshell This review looked at the effect of a fiber-rich diet on the microbiome for patients with diabetes. It found that high-fiber diets led to more healthy bacteria in the gut, and may improve glucose control. Some background The microbiome consists of bacteria and other microorganisms which live on the skin and in the gut. A healthy gut...
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In a nutshell This study used real-world data to compare SGLT-2 inhibitors versus other medications for patients with type 2 diabetes (T2D). It found that SGLT-2 inhibitors led to lower kidney disease and better overall outcomes. Some background T2D is a condition in which the body cannot effectively lower the amount of glucose (sugar) in the blood....
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In a nutshell This review looked at how SGTL2 inhibitors with or without metformin (Glucophage) affect heart and kidney health for patients with type 2 diabetes (T2D). It found that these medications improve cardiovascular and kidney outcomes, whether or not patients are also taking metformin. Some background SGLT2 inhibitors are a group of T2D...
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In a nutshell This study compared the traditional diabetic diet (TDD) with a low-carbohydrate diet (LCD) for patients with poorly controlled type 2 diabetes (T2D). They found that the LCD resulted in better blood glucose (sugar) control and reduced need for diabetic medications compared to the TDD. Some background The traditional...
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