In a nutshell This article looked at the potential benefits of using L-carnitine following a heart attack. Some background L-carnitine is a protein involved in the processing of fatty acids in the body. Cells in our bodies use fatty acids to produce energy. During a heart attack, levels of L-carnitine in the heart muscle become depleted. This...
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Using alternative antiplatelet drugs in patients intolerant to aspirin after stenting
In a nutshell This study investigated whether patients with aspirin intolerance could receive an alternative antiplatelet medication after coronary angioplasty with stenting. Some background Patients who undergo a stenting procedure to dilate the blood vessels leading to the heart (coronary arteries) need to take drugs that prevent blood clots...
Read MoreOutcomes following coronary stenting with different drug-eluting and bare-metal stents
In a nutshell This article analyzed data currently available regarding the outcomes using different types of stents to restore circulation through the coronary arteries following a heart attack. Researchers compared the use of bare-metal stents and drug-eluting stents (first and second generation). Some background Stenting is a procedure done as...
Read MoreBlood pressure targets in patients with a coronary artery disease
In a nutshell This article compares two approaches to blood pressure reduction in patients with coronary artery disease (CAD): intensive and standard. The incidence of heart failure, strokes, and cardiovascular-related deaths were compared between patients who received either therapy. Some background CAD is a condition caused by the narrowing of...
Read MoreDrug-eluting stents are equally safe and more efficacious than bare-metal stents for patients with a coronary artery disease
In a nutshell The present article draws a comparison between various subtypes of drug-eluting stents (DES) and bare metal stents (BMS), evaluating their safety and efficacy. Some background Coronary artery disease (CAD) is a heart condition caused by the narrowing of the coronary arteries which nourish the heart. This in turn causes a restriction...
Read MoreComparison between two strategies for the prevention of heart attack in stable coronary artery disease
In a nutshell The present study compares the effectiveness of two approaches – conservative and interventional – with relation to heart attack prevention in patients with a stable coronary heart disease (CAD). The conservative strategy consists of optimal drug therapy; the interventional approach is based on percutaneous coronary...
Read MoreNitrates as part of medical therapy and cardiac rehab for patients with chronic chest pain
In a nutshell In this article, the use of nitrates in patients with coronary artery disease is reviewed in details. Both the benefits and limitations of nitrate therapy are discussed, as well as the effect of nitrate therapy on cardiac rehabilitation. Some background CAD (Coronary Artery Disease) is a major cause of death worldwide, but also...
Read MoreBenefits of calcium channel blockers for patients with cardiovascular diseases
In a nutshell This meta-analysis combines the results of several studies that addressed the benefits of calcium channel blockers (CCBs) in treating cardiovascular conditions. CCBs were compared to other drugs for their ability to reduce the rate of death from any cause; death from cardiac disease; cardiovascular events (e.g. heart attack,...
Read MoreComparing treatment options for patients with coronary artery disease and diabetes
In a nutshell This study compared the outcomes of two interventional procedures for multivessel coronary artery disease, coronary artery-bypass grafting (CABG) and percutaneous coronary intervention (PCI) in patients with diabetes mellitus (DM). Some background Coronary artery disease (CAD) is a condition caused by the narrowing of the blood...
Read MoreThe SNYTAX score II may be used to guide decision making between PCI and CABG
In a nutshell The SYNTAX score was designed to assess the severity of coronary artery disease (CAD). However, this score has not aided doctors in assessing whether a CAD patient would benefit more from percutaneous coronary infusion (PCI) or coronary artery bypass graft (CABG). Here, researchers develop a new scoring system. The new system uses some...
Read MoreWhat is the preferable treatment for stent restenosis?
In a nutshell This study compared the outcomes of two new percutaneous coronary intervention (PCI) treatments for recurring coronary artery disease, a paclitaxel-eluting stent and a paclitaxel-eluting balloon. Some background Coronary artery disease (CAD) is the gradual (sometimes sudden) narrowing of the arteries that supply heart muscle...
Read MoreCardiac rehabilitation after heart attack: is it helpful?
In a nutshell This comprehensive rehabilitation trial evaluated the benefit, if any, of cardiac rehablitation on survival, cardiac or psychological wellness, and general well-being in heart attack survivors. Some background Myocardial Infarction(MI) or heart-attack occurs when flow of oxygen-rich blood is suddenly blocked from reaching the...
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