In a nutshell This study investigated which blood pressure lowering drug, perindopril or lisinoril, is better at reducing the occurence of death caused by high blood pressure and heart problems over a 5 year period in patients with high blood pressure. Some background Hypertension (high blood pressure) is a common medical condition where...
Read MoreIn a nutshell This study investigated whether atrial fibrillation (an abnormal heart rhythm) increases the risk of heart attack among patients with coronary heart disease. Some background Atrial fibrillation is an irregular heart beat condition that may cause blood to pool and clot. If a blood clot forms it can be pumped to an artery that supplies...
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In a nutshell This study investogated factors that are associated with poor prognosis (disease outcome or course) among coronary artery disease patients. Some background Coronary artery disease is a common medical condition caused by the narrowing of blood vessels that supply the heart with blood, oxygen and nutrients. Coronary...
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In a nutshell This study involved heart attack patients who had more than one heart artery blocked and investigated whether is was safer to surgically treat all of the blocked arteries or only treat the main artery causing the heart attack. Some background A heart attack occurs when blood flow to the heart is blocked. This mostly occurs...
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In a nutshell This study investigated whether environmental cigarette smoke caused oxidative stress in patients that had experienced a heart attack Some background Oxidative stress refers to when there is a high level of oxidants in the body. Oxidants are produced as part of a normal process when we breathe in oxygen, but air pollution, smoking,...
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In a nutshell This study investigated what the best oral blood thinning drug treatment is for patients with sudden decreased blood flow to the heart, a condition also known an acute coronary syndrome. Some background Acute coronary syndrome is a term used for any condition caused by a sudden reduced blood flow to the heart. Acute coronary...
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In a nutshell This study compared the effectiveness and safety of two third-generation stents to see whether one was better than the other. Some background Stent angioplasty or percutaneous coronary intervention (PCI), is surgery carried out on patients with coronary artery disease. Coronary artery disease refers to...
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In a nutshell This study looked at whether high blood pressure drugs, angiotensin converting enzyme inhibitors, reduce the risk of new-onset type-2 diabetes. Some background Diabetes, or diabetes mellitus, is a disease that results in uncontrolled high blood sugar. High blood sugar occurs mainly due to the body not producing insulin (type-1...
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In a nutshell This study looked at the effectiveness and safety of biolimus-eluting stents with 6 months antiplatelet therapy among patients with coronary artery disease. Some background Stenting (balloon angioplasty) is a surgery carried out on patients with coronary artery disease. Coronary artery disease refers to a...
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In a nutshell This study looked at whether long-term treatment (52 weeks) with pitavastatin is safe and effective at managing cholesterol among patients with cardiovascular disease. Some background Cardiovascular disease generally refers to conditions that involve narrowed or blocked blood vessels that can lead to a heart attack,...
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In a nutshell This study looked at the safety and effectiveness of the Resolute zotarolimus-eluting stent after 1 year in patients with coronary artery disease. Some background Stenting (balloon angioplasty) is a surgery carried out on patients with coronary artery disease. Coronary artery disease refers to a condition caused...
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In a nutshell This study looked at whether stent length affects clinical outcomes after drug-releasing (eluting) stent implantation. Some background Stenting (balloon angioplasty or percutaneous coronary intervention) is a surgery carried out on patients with coronary artery disease. Coronary artery disease refers to a condition...
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