In a nutshell This paper looked at effect of statin treatment after heart attack in elderly patients. Patients who started statin treatment did not have differences in cognition and physical abilities compared to patients who did not start statin treatment. Some background Statins are a group of drugs that work to reduce levels of...
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About heart disease in women
In a nutshell This paper reviews the diagnosis and treatment of cardiovascular disease in women. Some background Cardiovascular disease (CVD) refers to diseases affecting the heart and blood vessels. It is the leading cause of death in females in the United States. It is important to study the risk factors, as CVD and its complications (such...
Read More5-Year outcome of a bioresorbable stent
In a nutshell This paper studied the long-term outcomes from the implantation of a bioresorbable scaffold that releases everolimus in patients with coronary stenosis. The 5-year study found that the scaffold was safe for use. Some background Coronary stenosis refers to narrowing of the blood vessels that supply blood to the heart. This is...
Read MoreEffect of proton-pump inhibitor and dual anti-platelet therapy
In a nutshell This paper studied the impact of proton-pump inhibitors (PPI) on patients receiving dual anti-platelet therapy. They concluded that the use of proton-pump inhibitors when necessary was not associated with worse outcomes in patients receiving dual anti-platelet therapy. Some background Percutaneous coronary intervention is a...
Read MoreChanges in risk factors in patients with and without acute coronary syndrome
In a nutshell This paper studied risk factors in patients with and without acute coronary syndrome who are undergoing percutaneous coronary intervention. The authors concluded that there were differences in risk factors between patients with or without acute coronary syndrome. Some background In cardiovascular disease, blood vessels are...
Read MoreLong-term prasugrel versus clopidogrel treatment for stroke prevention
In a nutshell This paper compared prasugrel and clopidogrel in the treatment of patients with acute coronary syndrome. Results suggested that prasugrel could be potentially beneficial over the long term in patients with acute coronary syndrome. Some background Acute coronary syndrome refers to situations where blood supplying the heart is blocked....
Read MoreDoes percutaneous coronary intervention improve long-term survival?
In a nutshell This paper studied the effect of percutaneous coronary intervention (PCI) on survival in patients with ischemic heart disease. The authors concluded that there was no long-term difference in survival in patients who had initial PCI plus medical therapy and patients who had medical therapy only. Some background In patients with...
Read MoreIs saxagliptin safe for type 2 diabetes patients with cardiovascular disease?
In a nutshell This paper studied the heart-related safety and efficacy of saxagliptin (Onglyza) in patients with type 2 diabetes. The authors concluded that saxagliptin did not improve the risk of cardiovascular disease. Some background Patients with type 2 diabetes mellitus have elevated levels of glucose (sugar) in...
Read MoreIs saxagliptin safe for type 2 diabetes patients with cardiovascular disease?
In a nutshell This paper studied the heart-related safety and efficacy of saxagliptin (Onglyza) in patients with type 2 diabetes. The authors concluded that saxagliptin did not improve the risk of cardiovascular disease. Some background Patients with type 2 diabetes mellitus have elevated levels of glucose (sugar) in...
Read MoreEffectiveness of perindopril and beta-blockers in patients with stable coronary artery disease
In a nutshell This paper studied whether adding perindopril (Aceon) to beta-blocker therapy could improve outcomes for patients with coronary artery disease. This study found that adding perindopril to beta-blocker therapy improved outcomes in patients with stable coronary artery disease. Some background Coronary artery disease occurs when...
Read MoreOutcome of cilostazol plus aspirin after PCI
In a nutshell This paper studied the outcome of adding cilostazol (Pletal) to aspirin in patients undergoing percutaneous coronary intervention. The authors found that this reduced rates of heart attack, stroke or revascularization. Some background Percutaneous coronary intervention is a procedure done to improve blood flow in blocked blood...
Read MoreSurvival following coronary artery bypass grafting (CABG) in patients with diabetes
In a nutshell This study investigated long-term survival in patients with type 1 and type 2 diabetes following coronary artery bypass grafting (CABG). The study concluded that patients with type 1 diabetes had more than double the long-term risk of death after CABG compared with patients without diabetes. The long-term risk of death in patients...
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