In a nutshell The aim of this study was to compare the effectiveness of angiotensin-converting enzyme inhibitors (ACEI) and angiotensin II receptor blockers (ARBs) in protecting the heart in patients with diabetes that have had a heart attack and who had stents placed. The main finding of the study was that ACEI reduced the risk of major adverse...
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In a nutshell This study investigated if short-term dual antiplatelet therapy (DAPT) improves outcomes after percutaneous coronary intervention (PCI). They found that short-term DAPT did not increase the risk of heart attacks or clots after PCI. Some background Patients with coronary artery disease (CAD) may have blockages in the arteries supplying...
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In a nutshell This study investigated if heart rate can predict the success following a percutaneous coronary intervention (PCI). They found that a higher heart rate (HR) before PCI was linked to a short-term risk of major adverse cardiac events (MACE; stroke, heart attack or death due to heart disease). Some background Coronary artery disease...
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In a nutshell This study investigated if clopidogrel (Plavix) and aspirin are effective when taken together for treating coronary artery disease (CAD). They found that clopidogrel and aspirin improved CAD symptoms compared to aspirin alone. Some background Coronary artery disease (CAD) is caused by reduced blood flow to the heart. This leads...
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In a nutshell This study investigated if bisoprolol (Zebeta) is safe and effective for long-term angina treatment. They found that bisoprolol was effective and well-tolerated long-term. Some background Angina is chest pain caused by reduced oxygen supply to the heart. Reduced blood flow to the heart can be caused by blockages in vessels...
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In a nutshell This study investigated the effects of the drug combination perindopril and amlodipine (PEAM) on organ damage in patients with hypertension and ischemic heart disease (IHD). They found that PEAM was effective in reducing blood pressure and organ damage in these patients. Some background Hypertension or high blood pressure (BP) is a...
Read MoreIn a nutshell This study investigated if there is a link between depressive symptoms and sudden death in patients with coronary heart disease (CHD). They found that patients with depressive symptoms have a higher risk of sudden cardiac death. Some background Coronary heart disease (CHD) is caused by reduced blood flow to the heart. There are a...
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In a nutshell This study investigated if dipyrone interacts with aspirin in patients with coronary heart disease (CHD). They found that dipyrone interferes with aspirin and should be used with caution in patients with CHD. Some background Coronary heart disease (CHD) is caused by reduced blood flow to the heart. This can be caused by a number of...
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In a nutshell This study investigated the long-term outcomes of coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) to treat coronary heart disease (CHD). They found that CABG was associated with a longer-term benefit than PCI. Some background Coronary heart disease (CHD) is caused by blockages to the vessels...
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In a nutshell This study investigated if ranolazine (Ranexa) improved angina symptoms and blood flow. They found that ranolazine improved angina symptoms and blood flow in patients with reduced coronary (blood vessels that supply the heart) flow. Some background Angina is the term for chest pain. Chest pain usually arises when the flow of...
Read MoreIn a nutshell This study investigated if revascularization (RV) is more effective than medical treatment (MT) in patients with silent myocardial ischemia (SMI). They found that RV was more effective than MT at reducing the risk of death in these patients. Some background Coronary heart disease (CHD) is a major cause of death worldwide. Myocardial...
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In a nutshell This study examined whether there was a link between low diastolic blood pressure (DBP) and the frequency of angina in patients with coronary artery disease (CAD; heart disease caused by a low blood supply to the heart because of hardened and narrowed blood vessels). The authors concluded that low DBP is associated with an increased risk of...
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