In a nutshell This study investigated if vitamin D levels are associated with angina. They found that low vitamin D deficiency (VitD) was associated with angina. Some background Coronary artery disease (CAD) describes a number of conditions that affect the heart and circulation. In CAD, patients experience reduced blood flow to the heart. One...
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Long-term outcomes of 3 different drug-releasing heart stents
In a nutshell The aim of this study was to compare the safety and effectiveness of 3 different drug-releasing stents for the heart blood vessels (biodegradable stents versus new permanent stents versus older permanent stents) after 10 years. The main finding of the study was that biodegradable and new permanent stents showed similar results and were...
Read MoreHappy Heart Health Day!
“The best and most beautiful things in the world cannot be seen or even touched–they must be felt by the heart.” ~Helen Keller “Wherever you go, go with all your heart.” ~Confucius Today celebrates the heart. Today also celebrates heart donors. “In Living On Through Organ Donation,” we shared the story of an amazing...
Read MoreVitamin D deficiency and cardiovascular health: is there an increased risk of injury?
In a nutshell This study investigated if vitamin D deficiency (VDD) is associated with subclinical myocardial injury (SC-MI) in patients with cardiovascular disease (CVD). They found that VDD is linked to SC-MI, particularly in men. Some background Cardiovascular disease (CVD) can be caused by a number of factors. Poor diet is a risk factor...
Read MoreSearching for patients with coronary artery disease to test a new medication
In a nutshell This phase 3 trial will determine if bempedoic acid (BPDA) reduces the risk of cardiovascular events (CVEs) in statin-intolerant (ST-IT) patients. The main outcome will be the time taken for a CVE to occur. The details Cardiovascular disease (CVD) is a serious condition that can lead to serious events (CVEs). CVEs include heart...
Read MoreCan a big first dose of atorvastatin lower poor outcomes in patients with heart attacks?
In a nutshell The aim of this study was to investigate if a large first dose (loading dose) of atorvastatin (Lipitor) can reduce major adverse cardiovascular events (MACE) in patients with heart attacks and unstable angina. Some background Acute coronary syndrome (ACS) is a term which describes heart attacks and unstable angina A heart attack is a...
Read MoreDiastolic blood pressure can predict the size of plaque in heart blood vessels
In a nutshell The aim of this study was to investigate the relationship between blood pressure and plaque size in coronary (heart) blood vessels. The main finding of the study was that diastolic (the second number in the blood pressure reading) blood pressure can predict the size of the coronary plaque. Some background High blood pressure is a major...
Read MoreLooking for patients with coronary artery disease to test a new stent
In a nutshell This trial is examining the effectiveness of a new drug-releasing stent, Svelte, for the treatment of coronary heart disease (CAD). The main outcome to be measured will be target lesion failure (heart attack/death due to blockage in the blood vessel that has the stent) 12 months later. This study is being conducted in the...
Read MoreThe FIREHAWK: a new stent for patients with coronary artery disease
In a nutshell The aim of this study was the compare the safety and effectiveness of the new FIREHAWK stent to the XIENCE stent in the management of coronary artery disease. The study found that the FIREHAWK was not inferior to the XIENCE stent at 12 months. Some background Coronary artery disease (CAD) means that the blood vessels to the heart become...
Read MoreAerobic exercise reduces the amount of fat in the blood in patients with heart disease
In a nutshell The aim of this study was to investigate the relationship between aerobic exercise and fat in the blood (triglycerides) in patients with heart disease. The main finding of the study was that aerobic exercises reduced triglycerides in these patients. Some background It was previously thought that LDL cholesterol (bad cholesterol) was...
Read MoreCholesterol levels and management of high cholesterol in patients with heart disease
In a nutshell The purpose of this study was to investigate the cholesterol levels and the management of high cholesterol in patients with acute coronary syndrome (heart attack/angina). Patients who had a STEMI (a specific type of heart attack) had worse cholesterol levels but had better cholesterol levels after 12 months of statin therapy. Some...
Read MoreLooking for patients who have had a recent heart attack to trial new smart technology to help prevent re-admission to hospital
In a nutshell This trial aims to test new smart technology for preventing patients who have recently had a heart attack from being readmitted to the hospital. The main outcome to be measured will be time to hospital re-admission within 30 days of discharge. This study is being conducted in Maryland, Massachusetts, and Pennsylvania, in the United...
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