In a nutshell This study compared the survival outcomes of different chemotherapy treatments in patients with inoperable advanced colorectal cancer (CRC). Researchers suggested that FOLFOXIRI plus bevacizumab (Avastin) significantly improved the survival of these patients. Some background Around 20% of patients present with advanced CRC at diagnosis....
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Bevacizumab plus mFOLFOX6 improves the outcomes of patients with colorectal cancer and liver metastasis
In a nutshell This study investigated the effects of bevacizumab (Avastin) combined with mFOLFOX6 (fluorouracil, leucovorin, and oxaliplatin) treatment in RAS-positive advanced colorectal cancer (CRC). Researchers suggested that this treatment improved the treatment and survival outcomes of patients with CRC and liver metastasis (spread to the...
Read MoreHepatic artery infusion improved the outcomes of patients with advanced colorectal cancer surgery
In a nutshell This study investigated the impact of hepatic artery infusion (HAI) after advanced colorectal cancer surgery in patients with liver metastasis. Researchers suggested that HAI is associated with improved outcomes in these patients regardless of KRAS mutation status. Some background Colorectal cancer is the third most common cancer...
Read MoreDoes chemotherapy after complete removal of rectal cancer improve outcomes?
In a nutshell This study investigated the differences in following the guidelines for advanced rectal cancer treatments. Researchers suggested chemotherapy after the complete removal of rectal cancer improves survival. Some background This year, an estimated 147,950 adults in the US will be diagnosed with colorectal cancer. Of these, 43,340 will be...
Read MoreLooking for participants to test a chemo-radiotherapy combination for operable rectal cancer
In a nutshell This trial is examining the effectiveness and safety of short-course radiation therapy and TAS-102 (Lonsurf) plus oxaliplatin (Eloxatin) chemotherapy in rectal cancer. The main outcome to be measured will be the change in treatment response. This study is being conducted in the US. The details Colorectal cancer is one of...
Read MoreLooking for participants to test a treatment combination for metastatic colorectal cancer
In a nutshell This phase 2 trial is examining the effectiveness of TAS-102 (Lonsurf) plus oxaliplatin (Eloxatin) in the treatment of metastatic (spread to other parts of the body) colorectal cancer. The main outcome to be measured will be the overall response to the treatment rate. This study is being conducted in New Jersey, US. The details...
Read MoreEvaluating long-term bowel function after low-anterior surgery for rectal cancer
In a nutshell This study investigated the long-term side effects of low anterior surgery for rectal cancer. Researchers suggested that radiation before surgery is associated with poorer bowel function after surgery. Some background Rectal cancer is a frequent and serious disease. In the US there are 43,340 new cases of rectal cancer every...
Read MoreStatins and Colorectal Cancer
Most people are taking statins to lower their cholesterol, right? It’s about reducing your risk of heart disease and stroke. Well, now there is some recent research that finds an association between taking statins and survival of a colorectal cancer diagnosis. This research is a review of almost 30,000 medical records from the National Veterans...
Read MoreCOVID-19 with Cancer
Recent research presented at a virtual meeting of the American Association for Cancer Research 1 indicates the need for greater care and continued social distancing for those who are in treatment for cancer and – in one study that was presented – those who have a recent history of cancer (the research looked at people from 2015 to the...
Read MorePanitumumab and capecitabine improves the outcomes of older patients with advanced colorectal cancer
In a nutshell This study investigated the effectiveness of panitumumab (Vectibix) and capecitabine (Xeloda) combination to treat older patients with advanced colorectal cancer (CRC). Researchers suggested that this combination is a good and safe treatment for older patients with CRC. Some background CRC is a common cancer worldwide. CRC patients are...
Read MoreCetuximab combined with chemotherapy improves the outcomes of patients with advanced colorectal cancer
In a nutshell This study investigated the effectiveness of cetuximab (Erbitux) in combination with chemotherapy for the treatment of advanced colorectal cancer (CRC). Researchers suggested that this combined treatment improves the outcomes of patients with CRC. Some background CRC is one of the most common cancers worldwide. Around 15 to 25% of...
Read MoreIs completion of irinotecan chemotherapy associated with better treatment response in locally advanced rectal cancer?
In a nutshell This study investigated the effectiveness of high completion of irinotecan (Camptosar) chemotherapy before locally advanced rectal cancer surgery. Researchers suggested that the completion of irinotecan chemotherapy was associated with better tumor response in these patients. Some background Colorectal cancer is the third most...
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