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High-dose rate intraoperative brachytherapy is associated with improved outcomes in patients with high-risk rectal cancer

High-dose rate intraoperative brachytherapy is associated with improved outcomes in patients with high-risk rectal cancer

Posted by on Apr 3, 2021 in Colorectal cancer | 0 comments

In a nutshell This study compared the effectiveness of electron beam radiotherapy (EBR) and high-dose brachytherapy (HDB) during surgery in patients with rectal cancer who underwent an incomplete removal of the cancer. Researchers suggested that HDB was associated with a lower risk of recurrence in these patients.  Some background Colorectal...

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Evaluating surgery and chemotherapy versus chemotherapy alone for the treatment of metastatic colorectal cancer.

Evaluating surgery and chemotherapy versus chemotherapy alone for the treatment of metastatic colorectal cancer.

Posted by on Mar 31, 2021 in Colorectal cancer | 0 comments

In a nutshell This study evaluated whether surgery of colorectal cancer (CRC) followed by chemotherapy (CT) improved the outcomes of patients with metastatic (spread) CRC compared to CT alone. The study found that there was no difference in patients' outcomes whether surgery was given or not. Some background CRC is the third most common cancer...

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CT-guided radioactive implant improves the outcomes of locally advanced rectal cancer

CT-guided radioactive implant improves the outcomes of locally advanced rectal cancer

Posted by on Mar 28, 2021 in Colorectal cancer | 0 comments

In a nutshell This study investigated the effectiveness and safety of computed tomography (CT)-guided radioactive 125Iodine (RI) implantation in patients with recurrent locally advanced rectal cancer (LARC). Researchers suggested that CT-guided RI implantation is a good and safe treatment for patients with LARC that came back...

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Is chemoradiotherapy before surgery needed for patients with stage II-III colorectal cancer?

Is chemoradiotherapy before surgery needed for patients with stage II-III colorectal cancer?

Posted by on Mar 14, 2021 in Colorectal cancer | 0 comments

In a nutshell This study evaluated whether chemoradiotherapy (CRT) before surgery improves the outcomes of patients with stage II-III colorectal cancer (CRC). The study found that CRT before surgery may not be needed in certain patients with low-risk disease. Some background CRC is the third most common cancer worldwide. The standard therapy for...

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Laparoscopic rectal cancer surgery provides safe oncological outcomes

Laparoscopic rectal cancer surgery provides safe oncological outcomes

Posted by on Mar 7, 2021 in Colorectal cancer | 0 comments

In a nutshell This study compared oncological adequateness (OA) and surgery outcomes between open and laparoscopic rectal cancer surgery. Researchers suggested that laparoscopic surgery (LS) is associated with good surgical and oncological outcomes. Some background Colorectal cancer is one of the most common cancers worldwide. Of these, 35% are rectal...

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Can reducing chemotherapy duration from 6 to 3 months reduce side effects in patients with colorectal cancer and still be effective?

Can reducing chemotherapy duration from 6 to 3 months reduce side effects in patients with colorectal cancer and still be effective?

Posted by on Mar 6, 2021 in Colorectal cancer | 0 comments

In a nutshell This study investigated if reducing therapy duration could reduce side effects in patients but still be effective in patients with stage II colorectal cancer (CRC). This study showed that in certain patients a 3-month treatment duration can be considered.  Some background Patients with colorectal cancer (CRC) can be treated...

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Comparing outcomes in robotic and open surgery for patients with rectal cancer

Comparing outcomes in robotic and open surgery for patients with rectal cancer

Posted by on Feb 26, 2021 in Colorectal cancer | 0 comments

In a nutshell This study compared the effectiveness of open surgery (OS) and robotic surgery (RS) in patients with rectal cancer. Researchers suggested that RS and OS provided similar treatment outcomes in these patients. Some background Colorectal cancer is one of the most common cancer worldwide. Rectal cancer makes up for one-third of these cases....

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How long should patients with locally advanced rectal cancer wait between chemoradiotherapy and surgery to achieve the best outcome?

How long should patients with locally advanced rectal cancer wait between chemoradiotherapy and surgery to achieve the best outcome?

Posted by on Feb 26, 2021 in Colorectal cancer | 0 comments

In a nutshell This study evaluated the timing between chemoradiotherapy (CRT) and surgery in patients with locally advanced rectal cancer (LARC). The study found that patients who had surgery more than 10 weeks after CRT had the best outcome. Some background Rectal cancer is commonly treated with surgery to remove the tumor. LARC is...

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Evaluating the effectiveness and safety of stereotactic ablative body radiotherapy in advanced cancer

Evaluating the effectiveness and safety of stereotactic ablative body radiotherapy in advanced cancer

Posted by on Feb 26, 2021 in Colorectal cancer | 0 comments

In a nutshell This study investigated the effectiveness and safety of stereotactic ablative radiation therapy (SABR) in the treatment of patients with oligometastatic (few metastases) cancer. The data showed that the use of SABR in these patients was associated with high overall survival and low toxicity. Some background Oligometastatic cancer (OMC)...

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Evaluating the use of radiotherapy followed by chemotherapy before surgery for locally-advanced rectal cancer.

Evaluating the use of radiotherapy followed by chemotherapy before surgery for locally-advanced rectal cancer.

Posted by on Feb 14, 2021 in Colorectal cancer | 0 comments

In a nutshell This trial looked at the use of short-course radiotherapy (RT) followed by chemotherapy (CT) and delayed surgery to reduce distant metastases (tumor spread) in patients with locally advanced rectal cancer (LARC). The trial found that this treatment was more effective in controlling distant metastases when compared to standard...

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What is the optimal duration of chemotherapy after surgery for patients with stage III colon cancer?

What is the optimal duration of chemotherapy after surgery for patients with stage III colon cancer?

Posted by on Feb 7, 2021 in Colorectal cancer | 0 comments

In a nutshell This trial looked at the length of adjuvant chemotherapy (AC; chemotherapy after surgery) for patients with stage III colon cancer. The authors found that 3 months of AC resulted in similar survival with reduced levels of toxicity, and cost compared to 6 months.  Some background AC has been standard care for patients with...

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