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Clarithromycin administered daily reduces the skin-related side effects associated with panitumumab treatment for metastatic colorectal cancer.

Clarithromycin administered daily reduces the skin-related side effects associated with panitumumab treatment for metastatic colorectal cancer.

Posted by on Sep 5, 2021 in Colorectal cancer | 0 comments

In a nutshell This study investigated the effectiveness and safety of preventative antibiotic treatment with clarithromycin (Biaxin) to prevent skin-related side effects associated with panitumumab (Vectibix) treatment for patients with metastatic colorectal cancer (mCRC). The data showed that clarithromycin administered daily along with a simple...

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Evaluating the effectiveness and safety of different bevacizumab schedules in combination with chemotherapy for the treatment of patients with metastatic colorectal cancer.

Evaluating the effectiveness and safety of different bevacizumab schedules in combination with chemotherapy for the treatment of patients with metastatic colorectal cancer.

Posted by on Aug 29, 2021 in Colorectal cancer | 0 comments

In a nutshell This study investigated the effectiveness and safety of bevacizumab (Avastin) administered either on the same day or a few days before chemotherapy for the treatment of patients with metastatic colorectal cancer (mCRC). The data showed that bevacizumab administered 4 days before chemotherapy significantly improved overall survival with...

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Comparing the safety and effectiveness of regorafenib versus TAS-102 for the treatment of patients with unresponsive metastatic colorectal cancer.

Comparing the safety and effectiveness of regorafenib versus TAS-102 for the treatment of patients with unresponsive metastatic colorectal cancer.

Posted by on Aug 7, 2021 in Colorectal cancer | 0 comments

In a nutshell This study evaluated the effectiveness and safety of regorafenib (Stivarga) versus TAS-102 (Lonsurf; trifluridine-tipiracil) for the treatment of patients with unresponsive metastatic colorectal cancer (mCRC). The data showed that both treatments were safe and lead to similar survival outcomes for primary and secondary treatment of...

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Evaluating outcomes of laparoscopic surgery for the treatment of elderly patients over 80 years with colorectal cancer.

Evaluating outcomes of laparoscopic surgery for the treatment of elderly patients over 80 years with colorectal cancer.

Posted by on Jul 31, 2021 in Colorectal cancer | 0 comments

In a nutshell This study evaluated the short- and long-term outcomes of laparoscopic surgery (LS; keyhole surgery) for the treatment of elderly patients with colorectal cancer (CRC) aged over 80 years. The data showed that LS is a good and safe option for these patients. Some background Colorectal cancer (CRC) is one of the most common types of cancer...

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Evaluating the effectiveness and safety of anlotinib for unresponsive metastatic colorectal cancer.

Evaluating the effectiveness and safety of anlotinib for unresponsive metastatic colorectal cancer.

Posted by on Jul 25, 2021 in Colorectal cancer | 0 comments

In a nutshell This study investigated the effectiveness and safety of anlotinib (AL3818) for the treatment of patients with unresponsive metastatic colorectal cancer (mCRC). The data showed that anlotinib was safe and significantly improved survival without cancer progression for these patients. Some background Colorectal cancer (CRC) is one of...

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Evaluating the effectiveness and safety of total neoadjuvant therapy versus standard neoadjuvant chemoradiotherapy for locally advanced rectal cancer.

Evaluating the effectiveness and safety of total neoadjuvant therapy versus standard neoadjuvant chemoradiotherapy for locally advanced rectal cancer.

Posted by on Jul 17, 2021 in Colorectal cancer | 0 comments

In a nutshell This study investigated the effectiveness and safety of total neoadjuvant therapy (TNT) versus standard neoadjuvant chemoradiotherapy (CRT) for the treatment of patients with locally advanced rectal cancer (LARC). The data showed that TNT was associated with improved outcomes compared with standard CRT for these patients. Some background...

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Evaluating the effectiveness and safety of chemotherapy before surgery for locally advanced colon cancer.

Evaluating the effectiveness and safety of chemotherapy before surgery for locally advanced colon cancer.

Posted by on Jul 11, 2021 in Colorectal cancer | 0 comments

In a nutshell This study investigated the safety, effectiveness, and side effect profile of chemotherapy given before surgery for the treatment of patients with locally advanced colon cancer (LACC). The data showed that this treatment was safe and effective with manageable side effects for these patients. Some background Colorectal cancer (CRC) is one...

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Percutaneous radiofrequency ablation improves the outcomes of patients with colorectal cancer liver metastases

Percutaneous radiofrequency ablation improves the outcomes of patients with colorectal cancer liver metastases

Posted by on Jul 9, 2021 in Colorectal cancer | 0 comments

In a nutshell This study investigated the effectiveness and safety of percutaneous radiofrequency ablation (PRA) in the treatment of colorectal cancer (CRC) liver metastases (LM). Researchers suggested that PRA is a good and safe method for the treatment of these patients.  Some background CRC is a common cancer worldwide, affecting 4.3% of...

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Does adding chemotherapy after surgery for liver metastasis improve the long-term outcome of patients with colorectal cancer?

Does adding chemotherapy after surgery for liver metastasis improve the long-term outcome of patients with colorectal cancer?

Posted by on Jun 6, 2021 in Colorectal cancer | 0 comments

In a nutshell The study investigated the impact of adding chemotherapy after surgery to remove liver metastasis on the outcomes of patients with colorectal cancer (CRC). The study reported a significantly longer survival in patients undergoing further chemotherapy. Some background Up to 50% of patients with CRC develop...

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FOLFIRINOX before pre-surgery treatment can improve the outcomes of patients with rectal cancer

FOLFIRINOX before pre-surgery treatment can improve the outcomes of patients with rectal cancer

Posted by on Jun 6, 2021 in Colorectal cancer | 0 comments

In a nutshell The aim of this study was to investigate FOLFIRINOX (oxaliplatin, irinotecan, leucovorin, and fluorouracil) before pre-surgery chemoradiotherapy (CRT) for patients with rectal cancer (RC). The study found that FOLFIRINOX given before CRT and surgery improved the outcomes of these patients. Some background RC can be treated with...

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Investigating herbal medicines to reduce chemotherapy related digestive side effects in patients with colorectal cancer

Investigating herbal medicines to reduce chemotherapy related digestive side effects in patients with colorectal cancer

Posted by on Jun 6, 2021 in Colorectal cancer | 0 comments

In a nutshell The aim of this study was to evaluate herbal medicines to treat gastrointestinal (GI) side effects in patients with colorectal cancer (CRC) treated with chemotherapy. The study found that herbal medicines reduced some GI side effects in these patients. Some background CRC can be treated with surgery to remove the tumor. In general,...

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Updates on the addition of radiotherapy for patients with locally advanced rectal cancer

Updates on the addition of radiotherapy for patients with locally advanced rectal cancer

Posted by on May 23, 2021 in Colorectal cancer | 0 comments

In a nutshell This study reviewed the role of the addition of radiation therapy (RT) for the treatment of locally advanced rectal cancer (LARC). Researchers suggested that radiation therapy during surgery is associated with a lower recurrence (when cancer comes back) rate.  Some background Locally advanced and locally recurrent rectal cancer are...

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