In a nutshell This study compared robotic and laparoscopic complete mesocolic surgery (CMS) in patients with colon cancer. Researchers suggested that both surgeries were safe and associated with excellent outcomes. Some background Colorectal cancer is the third most common cancer in the US. After the standard treatment, 30 to 40% of the patients...
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Re-treatment with cetuximab improves cancer outcomes in patients with inoperable colorectal cancer
In a nutshell This study investigated the effect of cetuximab (Erbitux) in patients with metastatic (spread to other parts of the body) colorectal cancer who did not respond to initial cetuximab treatment. Researchers suggested that this treatment may be beneficial in longer treatment durations. Some background The standard treatment for patients...
Read MoreRectal cancer: short- and long-term outcomes of robotic assisted laparoscopic surgery
In a nutshell This article investigated the short- and long-term outcomes of patients with rectal cancer who underwent robotic-assisted laparoscopic surgery (RALS). The authors concluded that RALS is beneficial and has good short- and long-term outcomes. Some background Conventional laparoscopic surgery (CLS; involves small cuts...
Read MoreThyroid hormones ratio can predict outcomes in patients with advanced colorectal cancer
In a nutshell This study investigated the impact of the thyroid hormones (TH) on survival outcomes of patients with colorectal cancer treated with regorafenib (Stivarga). Researchers suggested that TH ratio can predict the outcomes in these patients. Some background TH such as FT3 (free triiodothyronine) and FT4 (free thyroxine) are released...
Read MorePredictive factors for the treatment of metastatic colorectal cancer with panitumumab
In a nutshell This study investigated the effectiveness of panitumumab (Vectibix) and the predictive factors for the treatment of metastatic (spread to other parts of the body) colorectal cancer. Researchers suggested that this treatment was effective for these patients and that early tumor shrinkage and RAS mutation (permanent change) are...
Read MorePET-CT scanning in the early detection of metastasis in patients with colon cancer
In a nutshell This study investigated the positive effect of PET-CT (an imaging technique) evaluation after surgery in stage 3 colon cancer. Researchers suggested that early follow-up with PET-CT leads to early detection of metastasis (spread to other parts of the body) in patients with stage 3 colon cancer. Some background Stage 3 colon cancer...
Read MoreChemotherapy before surgery does not affect bowel function in patients with rectal cancer
In a nutshell This study investigated the effects of different therapies on bowel movements after surgery in patients with rectal cancer. Researchers suggested that chemotherapy alone does not affect the bowel function after rectal surgery. Some background In the past 20 years, advances in the treatment of rectal cancer improved outcomes and survival...
Read MoreIs regorafenib a safe option for the treatment of metastatic colorectal cancer?
In a nutshell This study investigated the effectiveness and safety of regorafenib (Stivarga) to treat patients with metastatic (spread to other parts of the body) colorectal cancer (mCRC) that progressed after initial treatment. Researchers suggested that regorafenib is a safe option to treat these patients. Some background The standard treatment...
Read MoreCan white blood-cell levels predict tumor response in rectal cancer?
In a nutshell This study investigated if a change in white blood cell (WBC) levels before or during chemotherapy and radiation therapy are associated with rectal tumor response. Researchers suggested that a decreased level of WBC is associated with improved tumor response in patients with rectal cancer. Some background Chemotherapy and radiation...
Read MoreOral mucositis caused by targeted therapy for colorectal cancer: which drug is safer?
In a nutshell This study investigated the frequency and severity of oral mucositis (OM) in patients with colorectal cancer treated with chemotherapy and panitumumab (Vectibix) or cetuximab (Erbitux). Researchers suggested that panitumumab ?is associated with increased levels of OM in these patients. Some background Colorectal cancer is the fourth...
Read MoreAdding mFOLFOX6 to the standard treatment for rectal cancer increases cancer response and survival
In a nutshell This study investigated whether adding mFOLFOX6 (modified; folinic acid, fluorouracil, and oxaliplatin) chemotherapy after standard chemotherapy and radiotherapy (CRT) and delaying surgery improves cancer response and survival in rectal cancer. Researchers suggest that this treatment increases disease-free survival (DFS;...
Read MoreLaparoscopic surgery is associated with improved quality of life in patients with colon cancer
In a nutshell This study compared open surgery to laparoscopic surgery (LS; a tube with a camera is inserted through a small cut to remove the tumor) in terms of quality of life in patients with colon cancer. Researchers suggested that patients treated with LS had an improved quality of life after surgery. Some background Colon cancer is...
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