In a nutshell This study compared two different types of chemotherapy for patients with metastatic (spread to other parts of the body) colorectal cancer (mCRC). Researchers suggested that FOLFOXIRI plus bevacizumab (Avastin) is associated with better outcomes in these patients. Some background Colorectal cancer is the third most common cancer...
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In a nutshell This study investigated the change in outcomes over 10-years in patients with stage 3 colon cancer who received FOLFOX chemotherapy. Researchers suggested that this treatment improved the outcomes of these patients. Some background Colorectal cancer is the third most common cancer diagnosed in both men and women in the US. The...
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In a nutshell This study examined the effects of granulocyte colony-stimulating factor (G-CSF) given as a preventative measure in patients with high- and medium-risk cancer receiving chemotherapy. The results showed that preventative G-CSF allowed more patients to complete chemotherapy treatment and lowered patients’ chances of developing secondary...
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In a nutshell This study investigated the cardiovascular effects of chemotherapy after colorectal cancer (CRC) surgery. Researchers suggested that this treatment increases the stiffness of blood vessels in patients with CRC. Some background Colorectal cancer is a major cause of cancer mortality. However, the mortality rate has decreased in the...
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In a nutshell This study investigated the role and optimal dose and duration of adjuvant (after surgery) chemotherapy (AC) in patients with locally advanced rectal cancer. Researchers suggested that this treatment was associated with improved survival in these patients. Some background Colorectal cancer is one of the most common cancers worldwide....
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In a nutshell This study investigated the effectiveness of cytoreductive surgery (CRS) in patients with colorectal cancer spread to the peritoneum (inner lining of the abdominal cavity). Researchers suggested that CRS is associated with improved survival in these patients. Some background Colorectal cancer is the third most common cancer worldwide. A...
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In a nutshell This study investigated the changes in fatigue (tiredness) severity in patients with rectal cancer undergoing treatment. Researchers suggested that fatigue gradually improves after treatment in these patients. Some background Colorectal cancer is the third most common cancer worldwide. It affects around 104,000 people every...
Read MoreIn a nutshell This study investigated tumor response and safety of intensity-modulated radiation therapy (IMRT) in anal cancer. Researchers reported an excellent response result and low short-term side effects for IMRT in these patients. Some background Colorectal cancer is one of the most common cancers worldwide. Anal cancer is a rare form of CRC...
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In a nutshell This study investigated the effectiveness of pelvic radiotherapy (PRT) followed by chemotherapy and surgery in advanced rectal cancer. Researchers suggested that this combined treatment is associated with improved survival rates. Some background Rectal cancer affects 44,180 people each year in the US. Up to 80% of these people present...
Read MoreIn a nutshell This study investigated the safety and effectiveness of TAS-102 (trifluridine-tipiracil) with and without bevacizumab (Avastin) therapy in metastatic colorectal cancer (mCRC). Researchers suggested that this combined therapy might be a good treatment option for patients with advanced CRC. Some background Colorectal cancer is the third...
Read MoreIn a nutshell This study investigated the effectiveness of chemotherapy after surgery in stage 2 colorectal cancer (CRC). Researchers suggested that this treatment may result in survival improvement but should be individualized. Some background CRC affects 145,600 adults in the US every year. Treatment for this disease is guided by stage at...
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In a nutshell This study investigated whether bevacizumab (Avastin) therapy and surgery of the tumor can improve the outcomes of patients with advanced colorectal cancer (CRC). Researchers suggested that patients treated with bevacizumab have better outcomes when undergoing surgery. Some background CRC is one of the most common cancers...
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