In a nutshell This study compared two different chemotherapy treatments in metastatic colorectal cancer (mCRC; spread to other parts of the body). Researchers suggested that 24-hour infused irinotecan (Camptosar) plus oral S-1 (Teysuno) chemotherapy and bevacizumab (Avastin) is well tolerated and associated with improved outcomes. Some background...
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In a nutshell This study compared the effectiveness and safety of two different chemotherapies in the treatment of advanced colorectal cancer (CRC). Researchers suggested that S1-based chemotherapy is a good option for the treatment of these patients. Some background CRC is one of the most common cancers worldwide. The standard treatment is surgery...
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In a nutshell This study examined how COVID-19 infection affects patients with cancer undergoing chemotherapy and the role of other factors in COVID-19 complications. The results showed that patients with advanced age and other medical conditions had a higher risk of COVID-19 complications but chemotherapy treatment did not need to be stopped. Some...
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In a nutshell This study investigated whether dezocine (Dalgan) could relieve depression symptoms after CRC surgery. Researchers suggested that this drug reduces depression after surgery and improves sleep quality in patients with CRC. Some background CRC is one of the most common cancers worldwide. The standard treatment is surgery and chemotherapy....
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In a nutshell This study investigated the effects of physical activity (PA) and long-term fatigue (tiredness) in patients with colorectal cancer. Researchers suggested that PA after the diagnosis is associated with less tiredness in these patients. Some background Colorectal cancer is the third most common cancer in men and the second in women...
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In a nutshell This study investigated the effectiveness of minimally invasive surgery in rectal cancer. Researchers suggested that less invasive surgery methods can result in better short-term outcomes in appropriately selected patients. Some background Colorectal cancer is the third most common cancer in the US. Rectal cancer comprises around 20% of...
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In a nutshell This study investigated the effectiveness of the combined treatment with cytokine-induced killer cell (CIKC) immunotherapy and chemotherapy after surgery in colorectal cancer. Researchers suggested that this therapy improves treatment outcomes in patients with colorectal cancer. Some background Colorectal cancer is one of the most common...
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In a nutshell This study investigated the effectiveness and safety of regorafenib (Stivarga) treatment in older patients with colorectal cancer (CRC). Researchers suggested that this treatment has similar effects in younger and older patients. Some background CRC is the third most common cancer worldwide. More than half are diagnosed in patients older...
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In a nutshell This study investigated the benefits of repeated cytoreductive surgery (CRS) and hyperthermic peritoneal chemotherapy (HIPEC) in patients with advanced colorectal cancer. Researchers suggested that repeated treatment improves the survival of patients with advanced colorectal cancer, without an increase in side effects. Some background...
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In a nutshell This study compared the effectiveness and safety of bevacizumab biosimilar (BE1040V) to the reference drug (Avastin) in the treatment of patients with metastatic colorectal cancer (mCRC). Researchers suggested that the effectiveness and safety of the biosimilar were similar to the reference drug bevacizumab. Some...
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In a nutshell This study investigated the frequency of late gastrointestinal (GI) side effects after radiation therapy (RT) for rectal cancer. Researchers suggested that after the improvement of RT methods these side effects are less frequent and less severe. Some background Colorectal cancer is one of the most frequently diagnosed cancers in the...
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In a nutshell This study investigated the effectiveness and safety of bevacizumab (Avastin) combined with chemotherapy in elderly patients with advanced colorectal cancer. Researchers suggested that this therapy might be associated with improved outcomes in fit older patients. Some background Colorectal cancer is the third most common cancer...
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