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Is a regimen of weekly chemotherapy with trastuzumab and pertuzumab as effective as standard treatment options for HER2-positive breast cancer

Is a regimen of weekly chemotherapy with trastuzumab and pertuzumab as effective as standard treatment options for HER2-positive breast cancer

Posted by on Aug 8, 2021 in Breast cancer | 0 comments

In a nutshell This study examined the use of paclitaxel (Taxol) and carboplatin (Paraplatin) as weekly chemotherapy (CT) with trastuzumab (Herceptin) and pertuzumab (Perjeta) in HER2+ breast cancer (BC) in order to reduce toxicity rates. The authors found that the weekly regimen of chemotherapy can be considered an alternative to standard chemotherapy...

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Aromatase inhibitors versus tamoxifen following chemotherapy for perimenopausal women with breast cancer

Aromatase inhibitors versus tamoxifen following chemotherapy for perimenopausal women with breast cancer

Posted by on Jul 31, 2021 in Breast cancer | 0 comments

In a nutshell This study was carried out to assess the use of aromatase inhibitors (AI) versus tamoxifen (Novaldex) for women before menopause with estrogen receptor-positive (ER+) breast cancer (BC). The authors found that AIs were associated with better outcomes than tamoxifen in these patients.  Some background About 80% of all BCs...

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Does neratinib plus capecitabine benefit patients with HER2-positive breast cancer spread to the central nervous system?

Does neratinib plus capecitabine benefit patients with HER2-positive breast cancer spread to the central nervous system?

Posted by on Jul 25, 2021 in Breast cancer | 0 comments

In a nutshell This study compared the safety and effectiveness of neratinib (Nerlynx) plus capecitabine (Xeloda) versus lapatinib (Tykerb) plus capecitabine in patients with human epidermal growth factor (HER2)-positive breast cancer (BC) spread (metastases) to the central nervous system (CNS; brain and spinal cord). The data showed that the...

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Is pyrotinib with vinorelbine effective in treating HER2+ metastatic breast cancer?

Is pyrotinib with vinorelbine effective in treating HER2+ metastatic breast cancer?

Posted by on Jul 21, 2021 in Breast cancer | 0 comments

In a nutshell This study was carried out to examine the safety and effectiveness of pyrotinib (Irene) in combination with vinorelbine (Navelibine) is in treating metastatic breast cancer (BC). The authors found that this treatment combination showed promising results and was well tolerated in these patients.  Some background BC is...

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Mental effects and depression induced by taxane-based chemotherapy in breast cancer survivors

Mental effects and depression induced by taxane-based chemotherapy in breast cancer survivors

Posted by on Jul 21, 2021 in Breast cancer | 0 comments

In a nutshell This study aimed to investigate depression and cognitive (thinking and reasoning) functions after taxane-based chemotherapy in patients with breast cancer.  This study concluded taxane-based chemotherapy commonly leads to cognitive impairment in these patients, but some functions improve or remain stable after stopping...

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Does exercise increase recovery in patients undergoing surgery for breast cancer?

Does exercise increase recovery in patients undergoing surgery for breast cancer?

Posted by on Jul 21, 2021 in Breast cancer | 0 comments

In a nutshell This study was carried out to examine the impact of physical activity (PA) on the recovery of patients having surgery for breast cancer (BC). The authors found that PA reduces the risk of patients developing chronic pain and women who had higher levels of PA recovered better than sedentary women.  Some background BC is one of...

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What is the best timing for chemotherapy after surgery in patients with early-stage breast cancer?

What is the best timing for chemotherapy after surgery in patients with early-stage breast cancer?

Posted by on Jul 11, 2021 in Breast cancer | 0 comments

In a nutshell This study looked at the timing of chemotherapy (CT) after surgery in the treatment of early breast cancer (BC). The authors found that CT given within 31 days after surgery may improve survival in patients with triple-negative (TN) BC.  Some background BC is one of the most common types of cancer found in women. There are...

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Comparing the safety and effectiveness of pyrotinib versus trastuzumab etamsine for the treatment of HER2-positive metastatic breast cancer.

Comparing the safety and effectiveness of pyrotinib versus trastuzumab etamsine for the treatment of HER2-positive metastatic breast cancer.

Posted by on Jul 11, 2021 in Breast cancer | 0 comments

In a nutshell This study compared the safety and effectiveness between pyrotinib (SHR-1258) and trastuzumab emtansine (T-DM1; Kadcyla) in patients with HER2+ metastatic breast cancer (BC) after previous treatment with trastuzumab (Herceptin) and chemotherapy. The data showed that pyrotinib may be more effective than T-DM1 for these patients. Some...

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Evaluating the effectiveness and safety of radiofrequency ablation for breast cancer smaller than 2 cm.

Evaluating the effectiveness and safety of radiofrequency ablation for breast cancer smaller than 2 cm.

Posted by on Jul 11, 2021 in Breast cancer | 0 comments

In a nutshell This study evaluated the effectiveness and safety of radiofrequency ablation (RFA) for breast cancer (BC) smaller than 2 cm. The data showed that RFA was safe and effective in these patients. Some background Radiofrequency ablation (RFA) is a medical procedure where pieces of tissue are removed using the heat that is produced from an...

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Effects of adherence to homone therapy after surgery and radiation on the outcomes of older patients with early-stage breast cancer

Effects of adherence to homone therapy after surgery and radiation on the outcomes of older patients with early-stage breast cancer

Posted by on Jun 13, 2021 in Breast cancer | 0 comments

In a nutshell This study aimed to investigate the effects of adherence to hormonal therapy (HT) and radiation on the outcomes of older patients with early-stage breast cancer (BC).   This study concluded that the lack of adherence to HT and omitting radiation can lead to poorer outcomes for these...

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Could patient-reported outcomes predict survival benefits in patients with advanced breast cancer treated with abemaciclib?

Could patient-reported outcomes predict survival benefits in patients with advanced breast cancer treated with abemaciclib?

Posted by on Jun 13, 2021 in Breast cancer | 0 comments

In a nutshell This study evaluated the association between patient-reported outcomes (PROs) and survival outcomes in patients with hormone receptor-positive (HR+)/HER2-negative (HER2-) advanced breast cancer (BC) treated with abemaciclib (Verzenio). The data showed that the PROs could be a predictor of survival benefits in these patients. Some...

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