In a nutshell This study was carried out to look at the risk of developing a second cancer in patients with breast cancer (BC) undergoing statin therapy. The authors found that there was little association between statin use and second cancer risk in these patients. Some background BC is one of the most common forms of cancer found in women. With...
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In a nutshell This study compared the effectiveness of breast-conserving surgery (BCS) to mastectomy (breast-removal surgery) after chemotherapy in patients with breast cancer. The authors found that BCS does not result in a lower survival in these patients. Some background BC is one of the most common forms of cancer in women. Standard care...
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In a nutshell This article aimed to examine the effectiveness of an immediate breast reconstruction (IBR) approach using DIEP-flap repair and compared it to the standard treatment of a delayed breast reconstruction (DBR) in women with breast cancer (BC) undergoing mastectomy (breast removal surgery). The authors concluded that IBR should be...
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In a nutshell This article looked at different types of non-drug therapies for the management of menopausal symptoms (MS) such as night sweats and hot flushes in breast cancer (BC) survivors. The authors concluded that cognitive-behavioral therapy (CBT) and hypnosis may offer some benefit for these women. Some background BC is the most common cancer...
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In a nutshell This trial was carried out to analyze whether the length of time without treatment and the length of time without active disease influences the survival of patients with advanced breast cancer (ABC) spread to the bone taking palbociclib (Ibrance) plus hormonal therapy (HT). The authors concluded...
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In a nutshell The study evaluated outcomes of lapatinib (Tykerb), trastuzumab (Herceptin), and aromatase inhibitor (AI) in postmenopausal women with human epidermal growth factor receptor 2-positive (HER2+) and hormone receptor-positive (HR+) metastatic breast cancer (MBC). The authors found that the combination was safe and effective in such...
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In a nutshell This trial was carried out to assess the effectiveness and safety of veliparib (ABT-888) in combination with carboplatin (Paraplatin) and paclitaxel (Taxol) in BRCA-mutated advanced breast cancer (BC). The authors found that the addition of veliparib to platinum-based chemotherapy resulted...
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In a nutshell This study investigated the effectiveness and safety of atezolizumab (Tecentriq) as an addition to chemotherapy before surgery for patients with early-stage triple-negative breast cancer (TNBC). The data showed that the combination is effective in improving treatment response in these patients. Some background...
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In a nutshell This trial was carried out to assess the long-term results of external-beam accelerated partial-breast irradiation (APBI) intensity-modulated radiation therapy (IMRT) compared to whole-breast irradiation (WBI) in early-stage breast cancer (BC). The authors found that the 10-year recurrence of breast tumors was similar between the 2 methods,...
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In a nutshell This study compared the survival rates for older patients with early-stage breast cancer (BC) receiving hormone therapy (HT), radiation (RT), both or none after breast-conserving surgery (BCS). The data showed that RT and HT in combination and RT alone may lead to higher survival expectancy than HT alone. Some...
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In a nutshell This trial was carried out to examine the use of recombinant human (rh) endostatin (EN) with CT before surgery in patients with breast cancer (BC). The authors concluded that the addition of EN to CT significantly improved the response rate to therapy and survival in these patients. Some background BC is the most common form of...
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In a nutshell This study examined the effectiveness and safety of the drug combination pertuzumab (Perjeta) and trastuzumab (Herceptin) as a treatment for breast cancer (BC) with positive HER2 (human epidermal growth factor receptor 2) before surgery to remove the tumor in a real-world setting. The data showed that this...
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