In a nutshell This study explored whether nanoparticle albumin-bound (nab) paclitaxel (Abraxane) is more efficient as chemotherapy before surgery compared to solvent-based (sb) taxanes in patients with breast cancer. The authors found that nab-paclitaxel was able to improve the outcomes of these patients. Some background Breast cancer...
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Can a healthy diet improve quality of life of women with breast cancer undergoing chemotherapy?
In a nutshell This study examined whether a healthy diet can improve the quality of life of women with breast cancer undergoing chemotherapy. The authors found that women who followed healthy dietary advice had an improvement in the quality of their life during chemotherapy, reducing nausea, vomiting, and increasing appetite. Some background...
Read MoreSexual Health, Communication and Cancer
“I think sexual health is at the intersection of mind/body & relationship factors. When sexual health is disrupted, it’s really important to figure out all the pieces…often folks only hear bits and pieces like “use lube” or “use it or lose it” & “we need a holistic approach!”[1] Dr. Sharon L. Bober,...
Read MoreEvaluating the effectiveness and safety of stereotactic ablative body radiotherapy in advanced cancer
In a nutshell This study investigated the effectiveness and safety of stereotactic ablative radiation therapy (SABR) in the treatment of patients with oligometastatic (few metastases) cancer. The data showed that the use of SABR in these patients was associated with high overall survival and low toxicity. Some background Oligometastatic cancer (OMC)...
Read MoreEvaluating breast removal surgery in stage IV inflammatory breast cancer.
In a nutshell This study looked at the use of modified radical mastectomy (MRM) in the treatment of newly diagnosed stage IV inflammatory breast cancer (IBC). The authors found that MRM is associated with improved survival in these patients. Some background IBC is a rare and aggressive cancer that affects 2.0-2.5% of women with BC....
Read MoreAdding S-1 to hormonal therapy in patients with ER+ HER2- breast cancer
In a nutshell This study investigated whether adding oral S-1 (Teysuno) to hormonal therapy improved outcomes in patients with estrogen receptor (ER)-positive and HER2-negative primary breast cancer (BC). The data showed that the combination of S-1 with hormonal therapy could be a potential treatment option for these patients. Some background...
Read MoreIs heart monitoring needed in patients with HER2-positive metastatic breast cancer using trastuzumab?
In a nutshell This article looked at the occurrence of heart-related side effects in patients with HER2-positive metastatic breast cancer (mBC) receiving trastuzumab (Herceptin). The authors found that non-smoking patients with a good heart function before receiving treatment have a low risk of heart toxicity (HT) after 4 years...
Read MoreControlling brain metastasis with localized radiotherapy.
In a nutshell This study evaluated the impact of radiotherapy (RT) on controlling brain metastasis (BM). The study suggested that a single dose of RT was effective in controlling small BM. Larger BM could be controlled more effectively with multiple rounds of RT. Some background The spread of cancer from the original tumor to other parts of the body...
Read MoreComparing partial breast irradiation and whole breast irradiation in patients with breast cancer
In a nutshell This article looked at the use of partial breast irradiation (PBI) versus whole-breast irradiation (WBI) as a treatment for breast cancer (BC). The authors found that PBI offered similar results when compared to WBI. Some background BC remains one of the most common forms of cancer found in women. Standard care for BC remains...
Read MoreCan circulating tumor cells help in improving the outcomes of patients with breast cancer?
In a nutshell This study evaluated the role of circulating tumor cells (CTCs) in deciding adjuvant therapy (AT; treatment after surgery) in patients with breast cancer (BC). This study showed that personalized AT based on CTCs improved patient survival. Some background BC that has not spread to other areas of the body is called non-metastatic...
Read MoreDoes the histological grade of early stage breast cancer effect outcomes of older women treated with breast conserving surgery?
In a nutshell This article was carried out to look at how histological grade (HG) impacts the outcomes of older women with early-stage (ES) breast cancer (BC) treated with breast-conserving therapy (BCS) with or without radiotherapy (RT). The authors found that the treatment of ESBC without RT resulted in a lower cancer-specific survival...
Read MoreReviewing treatments for genitourinary symptoms in breast cancer survivors
In a nutshell This review aims to discuss the current treatment options available for genitourinary (GU) symptoms related to menopause in breast cancer (BC) survivors. Some background Vulvovaginal atrophy (VVA; thinning, trying, and inflammation of the lining of the vagina) is one of the side effects of hormonal treatments given to patients with...
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