In a nutshell This study reported the long-term effectiveness and safety of adding isatuximab (Sarclisa) to carfilzomib (Kyprolis) and dexamethasone (Decadron) combination (Kd) for patients with previously treated relapsed multiple myeloma (MM). The data showed that over the long term adding isatuximab to the Kd regimen was effective with manageable side...
Read MoreEvaluating the effect of varicocele repair on sperm parameters in infertile men.
In a nutshell This study evaluated the effect of varicocele repair (VR) on sperm parameters in infertile men with clinical varicocele. The data showed that VR significantly increased the total sperm count, sperm motility (movement), morphology (shape), and concentration in these men. Some background Male infertility can be caused by a number of...
Read MoreEvaluating the functional and oncologic outcomes of combining whole-gland high-intensity focused ultrasound ablation with transurethral resection of the prostate in patients with prostate cancer.
In a nutshell This study evaluated the functional and oncologic outcomes of combining whole-gland high-intensity focused ultrasound ablation (HIFU) with transurethral resection of the prostate (TURP) in patients with prostate cancer (PCa). The data showed that the combination treatment of whole-gland HIFU and TURP improved the urinary outcomes in these...
Read MoreEvaluating the long-term effectiveness and safety of nivolumab plus ipilimumab versus nivolumab alone after surgery in patients with stage IV melanoma.
In a nutshell This study evaluated the effectiveness and safety of nivolumab (Opdivo) plus ipilimumab (Yervoy) versus nivolumab alone given after surgery in patients with stage IV melanoma. The data showed that both nivolumab plus ipilimumab and nivolumab alone after surgery were effective compared with placebo and significantly improved survival without...
Read MoreWhich type of aerobic training provides greater benefits to patients with type 2 diabetes?
In a nutshell This study examined the impact of three types of aerobic training exercises on measurements of heart and metabolic function in patients with type 2 diabetes (T2D). The data showed that greater improvements occurred in heart and breathing function measurements with low-volume high-intensity training (HITT) compared to low-volume...
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