In a nutshell This study evaluated the effectiveness and safety of ivabradine (Procoralan) in combination with beta-blockers in patients with stable angina. The data showed that the combination of ivabradine plus beta-blocker therapy effectively reduced heart rate, angina symptoms, and the use of short-acting nitrates from the first month of treatment...
Read MoreEvaluating the optimal treatment regimens given before and after surgery in improving survival outcomes in patients with HER2-positive breast cancer.
In a nutshell This study evaluated the optimal treatment regimens given before and after surgery in terms of improving the survival outcomes in patients with human epidermal growth factor receptor 2-positive (HER2+) breast cancer (BC). The data showed that chemotherapy plus trastuzumab (Herceptin) and pertuzumab (Perjeta) was the best treatment...
Read MoreEvaluating the effects of metformin and exenatide on pregnancy rate and pregnancy outcomes in overweight or obese infertile women with PCOS.
In a nutshell This study compared the effects of metformin (Glucophage) and exenatide (Byetta) on pregnancy rate and pregnancy outcomes in overweight or obese infertile women with polycystic ovary syndrome (PCOS). The data showed that 12 weeks of exenatide treatment before pregnancy improved spontaneous pregnancy in these women. Some background...
Read MoreEvaluating the effectiveness and safety of transanal versus laparoscopic total mesorectal resection for the treatment of patients with rectal cancer.
In a nutshell This study evaluated the effectiveness and safety of transanal (ta) versus laparoscopic (lap) total mesorectal resection (TME) for the treatment of patients with stage I-III rectal cancer (RC). The data showed that experienced surgeons can safely perform taTME in these patients. Some background Rectal cancer (RC) is one of the most...
Read MoreEvaluating the effectiveness of abemaciclib alone or in combination with tamoxifen in patients with HR+, HER2– metastatic breast cancer resistant to hormone therapy.
In a nutshell This study evaluated the effectiveness of abemaciclib (Verzenio) alone or in combination with tamoxifen (Nolvadex) in patients with hormone receptor-positive (HR+)/HER2-negative (HER2-) metastatic breast cancer (BC) resistant to hormone therapy. The data showed that abemaciclib in combination with tamoxifen was more effective in improving...
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