In a nutshell The study compared the effectiveness and safety of trastuzumab deruxtecan (TD; Enhertu) with trastuzumab emtansine (TE; Kadcyla) in patients with HER2-positive (HER2+) metastatic breast cancer (BC). The study found that TD was more effective and well-tolerated compared to TE in these patients. Some background HER2+ BC...
Read MoreEvaluating the effectiveness of decitabine combined with allogeneic hematopoietic stem cell transplantation for the treatment of patients with recurrent and refractory acute myeloid leukemia.
In a nutshell This study evaluated the effectiveness of decitabine (Dacogen) combined with allogeneic hematopoietic stem cell transplantation (allo-HSCT) for the treatment of patients with recurrent and refractory (r/r) acute myeloid leukemia (AML). The data showed that decitabine combined with allo-HSCT reduced the risk of recurrence and improved...
Read MoreEvaluating the effectiveness of progestin-primed ovarian stimulation protocol for infertile patients with different ovarian reserve functions.
In a nutshell This study evaluated the effectiveness of progestin-primed ovarian stimulation (PPOS) protocol for infertile patients with different ovarian reserve functions. The data showed that PPOS is an effective ovarian stimulation protocol and is beneficial for these patients. Some background Many couples with infertility opt to use assisted...
Read MoreDoes transcranial direct current stimulation improve speech production in patients with speech impairment after stroke?
In a nutshell This study evaluated the effectiveness of transcranial direct current stimulation (tDCS) on speech intelligibility, and speech-related physiological and vocal functions in dysarthric (speech impairment) patients after stroke. The data showed that tDCS enhanced the effects of traditional speech therapy in these patients. Some...
Read MoreEvaluating the effectiveness and safety of pembrolizumab for the treatment of patients with relapsed or refractory classical Hodgkin lymphoma before stem cell transplantation.
In a nutshell This study evaluated the effectiveness and safety of pembrolizumab (Keytruda) for the treatment of patients with relapsed or refractory (r/r) classical Hodgkin lymphoma (cHL) before stem cell transplantation. The data showed that pembrolizumab was effective and safe with manageable side effects in these patients. Some background...
Read More