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prostate cancer | Research | Treatment | 10 pages | source: JAMA network open | Added Sep 17, 2023

Does statin use improve survival outcomes in men with advanced prostate cancer undergoing androgen deprivation therapy?

This study evaluated the association between statin (cholesterol-lowering drugs) use and survival outcomes in men with advanced prostate cancer (PC) undergoing androgen deprivation therapy (ADT). The data showed that statin use improved the survival outcomes in these patients.

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prostate cancer | Research | Treatment | 10 pages | source: European Urology | Added May 18, 2023

Evaluating the effectiveness of degarelix with or without apalutamide before prostate surgery in patients with high-risk prostate cancer.

This study evaluated the effectiveness of degarelix (Firmagon) with or without apalutamide (Erleada) before radical prostatectomy (RP; prostate surgery) in patients with high-risk prostate cancer (PC). The data showed that degarelix plus apalutamide significantly improved the pathological response in these patients.

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prostate cancer | Research | Treatment | 10 pages | source: The Lancet. Oncology | Added May 16, 2023

Evaluating the effectiveness and safety of rezvilutamide versus bicalutamide in combination with androgen deprivation therapy for metastatic hormone-sensitive prostate cancer.

This study evaluated the effectiveness and safety of rezvilutamide (Ariane) versus bicalutamide (Casodex) in combination with androgen deprivation therapy (ADT) for the treatment of patients with metastatic hormone-sensitive prostate cancer (mHSPC). The data showed that rezvilutamide in combination with ADT significantly improved the survival outcomes compared with bicalutamide plus ADT with manageable side effects in these patients.

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prostate cancer | Research | Treatment | 10 pages | source: European Urology | Added May 13, 2023

Evaluating the benefits of radiotherapy dose escalation and the addition of short-term or long-term androgen deprivation therapy in men with localized prostate cancer.

This study evaluated the benefits of radiation therapy (RT) dose escalation and the addition of short-term (ST) or long-term (LT) androgen deprivation therapy (ADT) to RT in men with localized prostate cancer (PCa). The data showed that the addition of ST or LT-ADT to RT improved survival without metastasis in these patients, regardless of the RT dose.

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prostate cancer | Research | 10 pages | source: JAMA network open | Added Sep 17, 2022

Evaluating the bone mineral density screening rates and their association with fracture rates among older men with prostate cancer receiving androgen deprivation therapy.

This study evaluated the bone mineral density (BMD) screening rates and their association with fracture rates among older men with prostate cancer (PC) receiving androgen deprivation therapy (ADT). The data showed that BMD screening is associated with a lower major fracture risk in these patients.

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prostate cancer | Research | 10 pages | source: The Oncologist | Added Sep 03, 2022

Evaluating the impact of immunetherapy on COVID-19 outcomes in patients with cancer.

This study evaluated the impact of immune checkpoint inhibitors (ICIs) on COVID-19 outcomes in patients with cancer. The data showed that the use of ICI treatment before COVID-19 infection does not affect the disease severity or survival outcomes. This study supports the continued use of ICIs in cancer patients during the pandemic.

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prostate cancer | Research | 10 pages | source: The Oncologist | Added Sep 01, 2022

Evaluating depression, anxiety, and patterns of mental health care in patients with prostate cancer receiving hormone therapy

This study evaluated depression, anxiety, and patterns of mental health care in patients with prostate cancer receiving hormonal therapy such as androgen deprivation therapy (ADT). The data showed that almost half of the patients with prostate cancer receiving ADT diagnosed with depression do not receive a documented mental health treatment.

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prostate cancer | Research | Treatment | 10 pages | source: The Lancet. Oncology | Added Aug 14, 2022

Evaluating the benefits of adding androgen deprivation therapy to radiation therapy and extending its duration in men with localized prostate cancer.

This study evaluated the benefits of adding androgen deprivation therapy (ADT) to radiation therapy (RT) and the benefit of extending the duration of ADT in men with localized prostate cancer (PCa). The data showed that the addition of ADT to RT and extending the duration of ADT administered after RT significantly improved the survival without metastasis in men with localized PCa.

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prostate cancer | Research | 10 pages | source: The Lancet. Oncology | Added Aug 08, 2022

Evaluating the effects of olaparib on pain and the health-related quality of life in patients with metastatic castration-resistant prostate cancer.

This study evaluated the effects of olaparib (Lynparza) on pain and the health-related quality of life (HR-QoL) in patients with metastatic castration-resistant prostate cancer (mCRPC) with mutations (genetic abnormalities) in DNA repair genes. The data showed that treatment with olaparib was associated with a reduction in pain and improvement in HR-QoL compared with physician’s choice of hormone therapy in these patients.

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prostate cancer | Research | Treatment | 10 pages | source: The New England Journal of Medicine | Added Jul 16, 2022

Evaluating the effectiveness and safety of darolutamide in combination with androgen deprivation therapy and docetaxel for metastatic hormone-sensitive prostate cancer.

This study evaluated the effectiveness and safety of darolutamide (Nubeqa) in combination with androgen deprivation therapy (ADT) and docetaxel (Taxotere) for the treatment of metastatic hormone-sensitive prostate cancer (mHSPC). The data showed that darolutamide in combination with ADT and docetaxel significantly improved the overall survival of these patients.

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