The study compared the pregnancy rates for intrauterine insemination (IUI) and in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) in couples with unexplained infertility. The data concluded that IVF/ICSI is a better treatment option than IUI for unexplained infertility.

This study investigated the safety and effectiveness of different doses of asundexian (BAY 2433334) in patients with acute myocardial infarction (MI; heart attack) treated with dual antiplatelet therapy (DAPT). The data showed that asundexian 50 mg when added to DAPT inhibits blood clotting factor XIa by more than 90% without significantly increasing the risk of bleeding in these patients.

This review assessed the effect of vitamin B12 supplementation on clinical outcomes when used alone or combined with other treatments for diabetic peripheral neuropathy (PN). The authors concluded that a greater reduction of PN symptoms occurred with the use of B12 supplementation alone or in combination with other treatments compared to placebo.

This study evaluated the effects of carbohydrate-restricted diets and intermittent fasting (IF) in patients with obesity, type 2 diabetes (T2D), and hypertension (high blood pressure). The authors recommended that in adults with T2D, overweight or obesity, a moderately-low carbohydrate diet can be considered as a dietary regimen for blood sugar control and weight reduction. 

The study evaluated the effectiveness of injections of autologous endometrial cells (AEC) and platelet-rich plasma (PRP) in infertile women with a thin endometrium (uterine lining). The study found that PRP injections and injections of AEC suspended in PRP improved the cells and thickness of the endometrium.

This study compared the long-term outcomes of percutaneous coronary intervention (PCI) using everolimus (Afinitor)-eluting stents (Xience) versus coronary artery bypass grafting (CABG) in patients with multivessel coronary artery disease (CAD). The data showed that both treatments were associated with a similar risk of heart attack, stroke, and death over the long term in these patients. However, PCI increased spontaneous heart attacks and repeat revascularization compared to CABG in these patients.

This study investigated the safety and effectiveness of intermittent fasting (IF) for 3 non-consecutive days a week, over a period of 12 weeks in people with insulin-treated type 2 diabetes (T2D). The authors concluded that this dietary approach was safe and effective for controlling blood glucose, reducing total daily insulin requirements, and decreasing body weight in participants with T2D.

This study compared the occurrence of infections and identified their risk factors in patients with rheumatoid arthritis (RA) that were treated with tofacitinib (Xeljanz) against those given a tumor necrosis factor inhibitor (TNFi). The data showed that serious and non-serious infections were higher in patients that received tofacitinib compared to a TNFi.

This study evaluated the effectiveness and safety of high-dose rosuvastatin (Crestor) combined with telmisartan (Micardis) or amlodipine (Norvasc) on glucose metabolism in patients with atherosclerotic cardiovascular disease (ASCVD), hypertension (high blood pressure), and impaired fasting glucose (IFG or prediabetes). The data showed that telmisartan significantly reduced the fasting glucose levels to normal glucose levels and prevented the new onset of diabetes in these patients.

This study evaluated the effectiveness and safety of a shorter dual antiplatelet therapy (DAPT) duration after percutaneous coronary intervention (PCI) using drug-eluting stents (DES) in patients with acute or recent myocardial infarction (MI; heart attack) at high bleeding risk. The data showed that a shorter DAPT duration (1 month) significantly reduced the risk of bleeding compared with a long DAPT duration (minimum of 3 months) with similar risks of death or heart attacks in these patients.