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prostate cancer | Research | Treatment | 10 pages | source: The Lancet. Oncology | Added Feb 26, 2021

Evaluating the effectiveness and safety of stereotactic ablative body radiotherapy in advanced cancer

This study investigated the effectiveness and safety of stereotactic ablative radiation therapy (SABR) in the treatment of patients with oligometastatic (few metastases) cancer. The data showed that the use of SABR in these patients was associated with high overall survival and low toxicity.

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prostate cancer | Research | Treatment | 10 pages | source: European urology focus | Added Feb 21, 2021

Evaluating long-term outcomes after high-intensity focused ultrasound for prostate cancer

This study evaluated the long-term outcomes of patients who underwent whole-gland high-intensity focused ultrasound (HIFU) for non-metastatic prostate cancer. The data showed that HIFU has favorable outcomes in low- and intermediate-risk groups of patients.

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prostate cancer | Research | Treatment | 10 pages | source: Journal of Urology | Added Jan 19, 2021

Evaluating the effectiveness of enzalutamide plus androgen deprivation therapy in metastatic hormone-sensitive prostate cancer by pattern of metastatic spread

This study examined the impact of the pattern of metastatic spread on the effectiveness of enzalutamide in combination with androgen deprivation therapy (ADT) for the treatment of metastatic hormone-sensitive prostate cancer (mHSPC). The data showed that the combination has good outcomes in men with bone and/or lymph node metastases.

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prostate cancer | Research | Treatment | 10 pages | source: Frontiers in oncology | Added Jan 17, 2021

Evaluating combination therapies for metastatic hormone-sensitive prostate cancer.

This study was carried out to look at the use of combining radiotherapy (RT), systemic therapy (ST; whole-body treatment), and androgen deprivation therapy (ADT) for prostate cancer (PC) that is hormone-sensitive and has spread. The authors concluded that ADT plus RT led to better outcomes in patients with low-volume disease.

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prostate cancer | Research | Treatment | 10 pages | source: Cochrane database of systematic reviews | Added Jan 13, 2021

Evaluating the effects of abiraterone acetate in combination with androgen deprivation therapy for the treatment of metastatic hormone-sensitive prostate cancer.

This study examined the effects of abiraterone acetate (AA; Zytiga) in combination with androgen deprivation therapy (ADT) for the treatment of metastatic hormone-sensitive prostate cancer (mHSPC). The data showed that AA and ADT combination improves the outcomes in these patients.

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prostate cancer | Research | 10 pages | source: Cochrane database of systematic reviews | Added Dec 26, 2020

Reviewing the effects of bisphosphonates or RANKL-inhibitors for men with prostate cancer and bone metastases

The study summarized the outcomes of bisphosphonates and RANKL-inhibitors as supportive treatment in men with prostate cancer (PC) and bone metastases (BM). The authors recommended that a balance between the efficacy and safety of such therapies must be considered for preventing skeletal events in such patients.

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prostate cancer | Research | Treatment | 10 pages | source: Journal of clinical oncology | Added Dec 20, 2020

Should patients with prostate cancer get androgen deprivation therapy before or after radiotherapy?

This study compared the effectiveness of giving androgen deprivation therapy (ADT) before or after radiotherapy (RT) for prostate cancer (PCa). The study found that treatment with RT followed by ADT increased patient survival without the spread of the disease.

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prostate cancer | Research | 10 pages | source: JAMA network open | Added Dec 15, 2020

Does androgen-receptor inhibitor therapy increase the risk of falling and broken bones in patients with prostate cancer?

This study investigated if treating patients who have prostate cancer with androgen receptor inhibitors (ARIs) increased their risk of falling and breaking their bones. The study found that patients who received ARI were more likely to have a fall or fracture compared to other treatments.

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prostate cancer | Clinical Trial | Added Dec 14, 2020

Searching for patients with advanced prostate cancer to trial an experimental combination treatment.

This trial is looking to examine the safety and effectiveness of a new drug called CYH33 in combination with olaparib (Lynparza) for the treatment of advanced solid tumors including prostate cancer. The main outcomes that are to be measured are side effects and the response rate to the treatment. This trial is being carried out in Houston, Texas, US. 

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prostate cancer | Research | 10 pages | source: European Urology | Added Dec 12, 2020

Predicting response to chemotherapy in advanced prostate cancer – what can genes tell us?

This study investigated the presence of the gene TMPRSS2-ERG in patients with metastatic castration-resistant prostate cancer on treatment outcome with taxane-based chemotherapy. Researchers reported that TMPRSS2-ERG, as identified by blood tests, is a reliable predictors of treatment success with taxane-based chemotherapy.

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