The authors evaluated the safety and effectiveness of paclitaxel (Taxol) in combination with alisertib (MLN8237) for the treatment of advanced breast cancer (BC). The authors observed that a weekly, reduced dose of paclitaxel combined with alisertib improved the survival without cancer worsening in these patients.

This article reviewed the common side effects of estrogen deprivation during hormonal therapy for women with breast cancer and provided an update on alternative therapies to manage these symptoms.

This study reviewed the effectiveness of resistance exercise in patients with rheumatoid arthritis (RA). The data showed that resistance exercise can significantly improve disease activity in these patients.

This study investigated the effectiveness of Pilates compared with circuit-based exercise in reducing joint pain during hormone therapy for women with breast cancer. The data showed that Pilates was more effective than circuit-based exercise in reducing joint pain for these patients.

This study is searching for participants with advanced solid tumors including breast cancer to examine the safety and effectiveness of experimental drug avapritinib (AYVAKIT). The main outcomes to be measured are the response to treatment and side effects. This trial is being conducted in Texas, US.

This study compared the effectiveness and safety outcomes of radiotherapy (RT) after immediate autologous breast reconstruction (IABR) following breast-conserving surgery (BCS) in patients with breast cancer. The data showed that RT following IABR provided aesthetically satisfactory results with manageable side effects in these patients.

This study investigated the effectiveness of fulvestrant (Faslodex) as a first-line treatment for postmenopausal women with estrogen receptor-positive (ER+) metastatic breast cancer (BC) in a real-world setting. The data showed that the outcomes of these patients in the real-world setting were similar to clinical trials with manageable side effects.

This study compared the long-term effectiveness of integrated intensity-modulated radiation therapy (IMRT) and segmented 3D-conventional radiotherapy (3D-CRT) following breast-removal surgery (radical mastectomy) in patients with breast cancer (BC). The data showed that integrated IMRT reduced the recurrence rate in the long-term with manageable side effects when compared to segmented 3D-CRT.

This study assessed the link between smoking and seropositivity levels of specific autoantibodies in patients with rheumatoid arthritis (RA). The authors concluded that patients with RA who were current smokers had significantly higher seropositivity levels than those that never smoked.

This article looked at the safety and effectiveness of abemaciclib (Verzenios) plus hormonal therapy (HT) in older patients with hormone receptor-positive (HR+)/HER-2 negative (HER2-) advanced breast cancer (BC). The authors concluded that abemaciclib + HT was effective across all age groups and while higher rates of side effects were reported in older patients, these were manageable with dose changes.