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breast cancer | Research | Treatment | 10 pages | source: Breast Cancer Research and Treatment | Added May 19, 2019

Evaluating palbociclib for patients with previously treated breast cancer

This study evaluated how well palbociclib (Ibrance) works in patients with breast cancer who received multiple lines of previous therapy. This study found that palbociclib was effective for these patients.

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rheumatoid arthritis | Research | Treatment | 12 pages | source: Arthritis Research & Therapy | Added May 12, 2019

Are kidneys at risk? Serum creatinine levels in patients treated for active rheumatoid arthritis with tofacitinib

This study investigated creatinine levels in rheumatoid arthritis patients being treated with tofacitinib (Xeljanz, Jakvinus). It also examined whether there are increased kidney problems in these patients.

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rheumatoid arthritis | Research | 10 pages | source: Annals of the rheumatic diseases | Added May 10, 2019

Do certain drugs increase the risk of cervical cancer in women with rheumatoid arthritis?

This study examined the risk of cervical cancer in women with rheumatoid arthritis (RA) treated with tumor necrosis factor (TNF)-inhibitors. The study concluded that women with RA treated with TNF-inhibitors are at increased risk of cervical cancer. 

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breast cancer | Research | 10 pages | source: Medicine | Added May 09, 2019

What is the clinical benefit of anthracycline treatment in early breast cancer?

This study investigated the benefit of anthracyclines (ATCs) in early breast cancer. They found that this treatment was an effective treatment in patients with early breast cancer. 

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rheumatoid arthritis | Research | Treatment | 10 pages | source: Arthritis Research & Therapy | Added May 08, 2019

Can low disease activity be maintained in early rheumatoid arthritis without adalimumab?

This study investigated if low disease activity could be maintained in early rheumatoid arthritis following discontinuation of long-term adalimumab.

They found that the majority of patients that discontinued adalimumab maintained low disease activity after 3 years.

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rheumatoid arthritis | Research | Treatment | 10 pages | source: Annals of the rheumatic diseases | Added May 06, 2019

Do biological drug treatments for rheumatoid arthritis increase the risk of skin cancer?

The study looked at the association between biological drug treatment for rheumatoid arthritis (RA) and the risk of melanoma (skin cancer). The authors concluded that there was no increased risk of melanoma in RA patients receiving treatment with biologics.  

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rheumatoid arthritis | Research | 8 pages | source: Annals of the rheumatic diseases | Added May 04, 2019

Blood protein predicts future response to rheumatoid arthritis therapy

This study investigated whether MRP8/14 protein levels can predict rheumatoid arthritis patient response to biologic drug treatment.

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breast cancer | Expertise | 0 pages | source: NutritionFacts.org | Added May 03, 2019

Which is healthier? Vegetables that help block cell growth

That doesn’t mean some veggies aren’t better than others. Some of these vegetables target multiple cancers at the same time. So, using this groundbreaking new data, let’s play “Which is healthier?”

Imagine you’re standing in line at one of those custom made-to-order salad places, where you get to choose your lettuce, choose your toppings, then choose your dressing. Let’s assume you don’t have a strong family history of any particular cancer, and so, aren’t trying to hone in on avoiding one tumor over any other.

First, let’s choose our lettuce. Boston, endive, radicchio, romaine, or spinach? Which is healthier? Out of the five, spinach is #1 against breast cancer—remember, the farther down, the better it is at slowing down these cancer cells. #1 against brain tumors, #1 against kidney cancer, #1 against lung cancer, and pediatric brain tumors—that’s why we need to feed our kids spinach! #1 against pancreatic cancer, prostate cancer, and stomach cancer.

Now it’s not #1 overall; there are 16 vegetables more powerful at stopping stomach cancer growth than spinach. But out of those five salad greens, spinach wins out across the board, against every cancer type tested.

What if the salad place said they were out of spinach, though? Which comes in second, out of the four left to choose from? For breast cancer, radicchio is #2. Against brain tumors? Radicchio. Kidney cancer? Radicchio. Radicchio, romaine, radicchio, radicchio, and radicchio. So, overall, out of those choices for greens, radicchio is second healthiest.

Back to the menu. Next, we get to choose four toppings. Now, there’s a long line of people behind you, all staring at us to make our choice. We don’t have time to ponder and pick the four absolute best, but we can at least make a guess as to roughly where on the graph they are.

Yes or no? According to this amazing new data, do carrots slow down cancer cell growth rates more than 50%? Yes or no? The answer is no. No, no, no, no, no, no, and no. So, shredded carrots aren’t going to make our top toppings choice.

What about shredded beets? Yes or no? Yes. Super yes! Brain tumor? Just beet it. Kidney cancer is a no; close to 50%, but not quite there. But then yes, yes, yes, yes, yes. So, overall, yes for beets.

Are we putting cucumber on our salad? As tasty as they may be, no. For most cancers it suppressed tumor cell growth less than 50%.

What about tomatoes? No tomatoes, either.

What about a potato? You can actually choose potatoes for your salad. Yes or no? No potatoes, either.

Wait a second; no iceberg lettuce, carrots, cucumbers, tomatoes, potatoes—that’s all people eat! That’s the problem. Even people eating their vegetables, aren’t really eating their vegetables. The majority of veggies people commonly eat have little effect.

Cutting to the chase: the line at the salad place is now out the door at this point. In this study, there was one clear winner. One vegetable that completely 100% stopped cancer growth in seven out of the eight tumor lines. One of the most important findings of the year. Which vegetable was it? Was it bok choy? Broccoli, Brussels sprouts, fiddlehead ferns, garlic, kale, or red cabbage?

#1 against breast cancer? Garlic. #1 against brain tumors? Garlic.#2 against kidney cancer: Garlic. Lung cancer? Garlic. Childhood brain tumors? Garlic. Pancreatic cancer? Garlic. Prostate cancer and stomach cancer? Garlic. So might I suggest a garlicky salad dressing?

But wait. Is it just that garlic is toxic to all cells? Yes, it stops the growth of cancer cells, but maybe it stops the growth of healthy cells, too? That wouldn’t be good. They tested for that. The black bars are the cancer cells; the white bars are the normal cells. As you can see, garlic slams cancer cells, but doesn’t touch normal cells, and the same thing with pretty much all the vegetables. They’re selective; they go after the cancer cells, but leave the normal cells alone. Veggies are amazing.

Now, if you didn’t pick garlic, and instead chose one of those others, you probably weren’t far off. The two best families of vegetables for cancer prevention are the cruciferous vegetables, like broccoli, kale, cabbage, and the allium family vegetables—like garlic, onions, and leeks. Let me just run through this one last time to highlight this important concept.

Starting from the beginning. Cruciferous vegetables in green; allium family vegetables in yellow. So what I want you to notice is the clustering of colors over to the right side, which illustrates the power of these two superfood classes of vegetables—whether for breast cancer, brain cancer, kidney cancer, lung cancer, or brain cancer.

Interestingly, you’ll notice that bok choy is often the kind of odd one out—apparently the least healthy of the cruciferous vegetables. Pancreatic cancer, prostate cancer, and finally, stomach cancer. So you know all those recipes that start with garlic and onions, and then throw you in some greens? That is the way to eat.

The researchers conclude: “The inclusion of cruciferous and Allium [family] vegetables in the diet is essential for effective dietary-based chemopreventive [or cancer-preventive] strategies.”

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rheumatoid arthritis | Research | Treatment | 10 pages | source: PLOS ONE | Added May 01, 2019

Anti-TNF therapy: Predictors of success

The study examined predictors of treatment success with anti-TNF drugs for rheumatoid arthritis (RA). The authors concluded that immune response and the presence of a protein in the blood can predict treatment outcomes with anti-TNF drugs.

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breast cancer | Research | Treatment | 10 pages | source: The Lancet. Oncology | Added Apr 30, 2019

Denosumab treatment in HR+ breast cancer

This study wanted to find out if adding the medication denosumab (Prolia, Xgeva) to cancer treatment for women with breast cancer reduces the risk of bone fractures. The study found that the patients treated with denosumab survived better, but there was no significant difference in the number of bone fractures.

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