This study aimed to explore the effects of melatonin in addition to pregabalin (Lyrica) for the management of painful diabetic neuropathy (PDN). The authors concluded that melatonin added to pregabalin may help in reducing pain related to PDN in patients with type 2 diabetes (T2D).

This study compared two heart interventions for people with coronary heart disease and type 2 diabetes (T2D). It found that coronary artery bypass grafting (CABG) led to better long-term outcomes than placing a stent in these patients.

The study compared the effectiveness and safety outcomes of darolutamide (Nubeqa) with apalutamide (Erleada) and enzalutamide (Xtandi) in treating non-metastatic castration-resistant prostate cancer (CRPC). The data showed that darolutamide was safer and had similar effectiveness compared to apalutamide and enzalutamide.

This study evaluated the effectiveness and safety of adding daratumumab (Darzalex) to pomalidomide (Pomalyst) and dexamethasone (Decadron) therapy for patients with previously treated relapsed or refractory (r/r) multiple myeloma (MM). The data showed that adding daratumumab to pomalidomide and dexamethasone regimen reduced the risk of disease progression or death for these patients.

This study looked at the timing of chemotherapy (CT) after surgery in the treatment of early breast cancer (BC). The authors found that CT given within 31 days after surgery may improve survival in patients with triple-negative (TN) BC. 

This article looked at the effectiveness and safety of continuous ixazomib (Ninlaro), thalidomide (Thalomid), and dexamethasone (Decadron) (ITd) in the treatment of relapsed and/or refractory (RR) multiple myeloma (MM). The authors found that this regimen was well tolerated and showed promising effectiveness in the treatment of RRMM.

This study aimed to investigate the effectiveness and safety of combining pembrolizumab (PEM; Keytruda)) and ipilimumab (IPI; Yervoy) for the treatment of advanced-stage melanoma in patients that have progressed after previous PD-1/L1 therapy. The study concluded that this combination was well tolerated and improved the outcomes of these patients. 

This study looked at remote screening for diabetic retinopathy (DR; eye disease) in a Japanese population. This study showed that remote screening for DR is an effective way of identifying patients who need ophthalmic intervention.

This study looked at 8 glucagon-like peptide-1 receptor agonists (GLP-1RAs) for the treatment of type 2 diabetes (T2D). They found that all 8 were more effective than placebo and there were no significant differences in safety.

This study examined the risk of heart-related mortality in patients undergoing androgen-deprivation therapy (ADT) for prostate cancer. It found that patients treated with radiation therapy and ADT did not have an increased risk of heart-related mortality.