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prostate cancer | Research | Treatment | 10 pages | source: Journal of nuclear medicine: official publication of the Society of Nuclear Medicine | Added May 31, 2022

Evaluating the effectiveness and safety of 225Ac-PSMA-617 after treatment with androgen deprivation therapy in patients with metastatic castration-resistant prostate cancer.

This study evaluated the effectiveness and safety of actinium-225 [225Ac]-PSMA-617 (225AcPSMA) after treatment with androgen deprivation therapy (ADT) in patients with metastatic castration-resistant prostate cancer (mCRPC). The data showed that 225AcPSMA treatment showed a higher response with manageable effects in these patients.

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prostate cancer | Research | 7 pages | source: Journal of Urology | Added Mar 17, 2022

Early EPIC score for urinary and sexual function predicts recovery after prostatectomy

This study evaluated whether the EPIC questionnaire can predict urinary and sexual functions one year after surgical removal of the prostate (radical prostatectomy) in patients with prostate cancer.

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prostate cancer | Research | Treatment | 10 pages | source: Urology | Added Mar 15, 2022

Prostate surgery versus radiation therapy: Comparing hospitalizations for treatment-related complications

This study compared the number of hospital admissions for treatment-related complications from prostate surgery and radiation therapy. Researchers reported higher rates of treatment-related hospitalizations following radiation therapy compared to surgery.

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prostate cancer | Research | Lifestyle | 9 pages | source: European Urology | Added Mar 13, 2022

Better physical functioning for survivors

The study evaluated the efficacy of sustained exercise training on improving physical functioning of long-term prostate cancer survivors.

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prostate cancer | Research | 9 pages | source: Journal of clinical oncology | Added Feb 22, 2022

Treatment options for localized prostate cancer – comparing long-term adverse effects

This study aimed to identify health-related decline in quality of life 4 to 8 years after prostate cancer (PC) treatment. Main finding: measures of quality of life vary based on therapy choice.

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prostate cancer | Research | 16 pages | source: European Urology | Added Feb 18, 2022

Potential Complications of Radiation Therapy for Prostate Cancer

This article reviewed the possible complications that can occur after radiation therapy for prostate cancer.

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prostate cancer | Research | Treatment | 8 pages | source: Journal of clinical oncology | Added Feb 16, 2022

Sexual, urinary, hormonal and bowel function – a comparison between prostate cancer survivors and noncancer men

The present study compared survivors of prostate cancer (PC) to patients of similar sexes and ages that have not had prostate cancer (non-cancer controls) based on the effects of prior treatments and treatment options on sexual, urinary, bowel and hormone functions. The main finding was that PC survivors had poorer sexual and urinary functions compared to non-cancer controls 10 years after diagnosis. 

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prostate cancer | Research | 10 pages | source: Neuroscience | Added Feb 12, 2022

Could neurogenesis be the key to understanding chemobrain?

Cognitive side effects to chemotherapy, often called “chemobrain” or “chemofog”, are a growing concern among cancer survivors. Symptoms such as a decline in memory, concentration and executive functions (such as organization or attention) are often described. Cognitive changes can cause significant distress and prevent a return to the quality of life experienced before treatment.

Recent studies have started to unravel the way chemotherapy agents affect the brain. Imaging of patients after chemotherapy show that treatments produce structural and functional changes in the brain. A number of explanations have been suggested for these changes after chemotherapy. Inflammatory changes in the brain, low hormone levels, or toxic destruction of nerve cells are a few examples.

Currently, there is no recognized treatment for cognitive dysfunction following chemotherapy. A greater understanding of the causes for cognitive decline will be key to finding ways of preventing or treating the effects of chemobrain.

Some studies have focused on the ability of the hippocampal region of the brain to form new nerve cells (called neurogenesis). Several cognitive and mood disorders, such as memory decline, fatigue and depression, have been linked to problems with neurogenesis.

Two recent studies investigating breast cancer patients focused specifically on the hippocampus. In one study, breast cancer survivors showed an average reduction of 8% in hippocampal size compared with healthy controls. Hippocampal shrinkage in this study was associated with the ability to retrieve facts from memory. Similarly, a second study found that the size of the hippocampus on the left side of the brain was reduced by nearly 7% in chemotherapy-exposed patients compared with healthy controls. Left hippocampal size was associated in this study with verbal memory performance (such as remembering words). Additional studies have also linked reduced hippocampus size in chemotherapy-exposed patients with deficits in figural and visual memory.

Only a few studies have reported chemotherapy-related effects on hippocampal function (rather than size). In all of these studies, activation of the hippocampus was less effecient and less functional in patients treated with chemotherapy.

Taken together, an increasing number of studies suggest that cognitive dysfunction following chemotherapy is associated with changes in the hippocampal region of the brain. Impaired hippocampal neurogenesis may be a contributing factor to cognitive decline, and key to preventing or treating chemobrain.

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prostate cancer | Medivizor | source: Medivizor | Added Feb 10, 2022

How Do I Tell My Child I Have Cancer? 7 Insights From Parents

A cancer diagnosis is overwhelming.  So is the prospect of telling your children about a cancer diagnosis. Social media makes it possible for parents to share strategies and provide guidance to others facing this challenge.  Here are some insights. Insight 1:  Tell Your Children the News Parents protect. The natural
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prostate cancer | Medivizor | source: Medivizor | Added Feb 06, 2022

Colon Cancer Patient Advocate Shares Her Story

In April, the American Association for Cancer Research (AACR) held a free education event on cancer called​ Progress and Promise Against Cancer in Washington, D.C.  Surrounded by experts in cancer research, Kim Hall Jackson shared her patient story. One evening in 2008, Jackson, an event planner, was running the mayor's

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