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colorectal cancer | Research | Treatment | 10 pages | source: The Lancet. Oncology | Added Apr 21, 2021

Survival of patients with rectal cancer followed-up by the watch and wait method after chemoradiotherapy

This study investigated the outcomes of patients with rectal cancer who were followed up with the watch and wait method after chemoradiotherapy (CRT). Researchers suggested that this strategy can effectively identify patients who can have a less frequent follow-up if they maintain response for the first 3 years after treatment.

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colorectal cancer | Research | Treatment | 10 pages | source: The Lancet. Oncology | Added Apr 11, 2021

Does adding chemotherapy to cytoreductive surgery improve the outcome of patients with peritoneal metastases from colorectal cancer?

This study evaluated the benefit of adding hyperthermic intraperitoneal chemotherapy (HIPEC) to cytoreductive surgery (CS) for the treatment of colorectal cancer (CRC) that has spread to the peritoneum (the lining of the abdomen that covers all abdominal organs). The study found that HIPEC added to CS did not improve the outcomes of these patients.

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colorectal cancer | Research | Treatment | 10 pages | source: International journal of radiation oncology, biology, physics | Added Apr 03, 2021

High-dose rate intraoperative brachytherapy is associated with improved outcomes in patients with high-risk rectal cancer

This study compared the effectiveness of electron beam radiotherapy (EBR) and high-dose brachytherapy (HDB) during surgery in patients with rectal cancer who underwent an incomplete removal of the cancer. Researchers suggested that HDB was associated with a lower risk of recurrence in these patients. 

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colorectal cancer | Research | Treatment | 10 pages | source: Journal of clinical oncology | Added Mar 31, 2021

Evaluating surgery and chemotherapy versus chemotherapy alone for the treatment of metastatic colorectal cancer.

This study evaluated whether surgery of colorectal cancer (CRC) followed by chemotherapy (CT) improved the outcomes of patients with metastatic (spread) CRC compared to CT alone. The study found that there was no difference in patients' outcomes whether surgery was given or not.

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colorectal cancer | Research | Treatment | 10 pages | source: Frontiers in oncology | Added Mar 28, 2021

CT-guided radioactive implant improves the outcomes of locally advanced rectal cancer

This study investigated the effectiveness and safety of computed tomography (CT)-guided radioactive 125Iodine (RI) implantation in patients with recurrent locally advanced rectal cancer (LARC). Researchers suggested that CT-guided RI implantation is a good and safe treatment for patients with LARC that came back after previous treatment.

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colorectal cancer | Research | 10 pages | source: Journal of clinical oncology | Added Mar 06, 2021

Can reducing chemotherapy duration from 6 to 3 months reduce side effects in patients with colorectal cancer and still be effective?

This study investigated if reducing therapy duration could reduce side effects in patients but still be effective in patients with stage II colorectal cancer (CRC). This study showed that in certain patients a 3-month treatment duration can be considered. 

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colorectal cancer | Research | Treatment | 10 pages | source: International Journal of Colorectal Disease | Added Feb 28, 2021

How long should patients with locally advanced rectal cancer wait between chemoradiotherapy and surgery to achieve the best outcome?

This study evaluated the timing between chemoradiotherapy (CRT) and surgery in patients with locally advanced rectal cancer (LARC). The study found that patients who had surgery more than 10 weeks after CRT had the best outcome.

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colorectal cancer | Research | Treatment | 10 pages | source: The Lancet. Oncology | Added Feb 26, 2021

Evaluating the effectiveness and safety of stereotactic ablative body radiotherapy in advanced cancer

This study investigated the effectiveness and safety of stereotactic ablative radiation therapy (SABR) in the treatment of patients with oligometastatic (few metastases) cancer. The data showed that the use of SABR in these patients was associated with high overall survival and low toxicity.

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colorectal cancer | Research | 10 pages | source: Colorectal Disease | Added Jan 27, 2021

What factors can influence ileostomy closure time after colorectal surgery?

This study evaluated reasons for a delay to ileostomy closure in patients who underwent anterior resection for rectal cancer. This study showed that factors such as having chemotherapy or cancer progression may delay ileostomy closure.

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colorectal cancer | Research | Treatment | 10 pages | source: The Oncologist | Added Jan 24, 2021

FOLFOXIRI-bevacizumab or FOLFOX-panitumumab for the treatment of left-sided metastatic colorectal cancer without RAS/BRAF mutations.

This study compared the use of chemotherapy and bevacizumab (Avastin) or panitumumab (Vectibix) for the treatment of left-sided metastatic colorectal cancer (mCRC) without BRAF/RAS mutations (permanent changes in genes). The study found that both treatment options are effective for these patients. 

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