This study investigated the effectiveness and safety of total neoadjuvant therapy (TNT) versus standard neoadjuvant chemoradiotherapy (CRT) for the treatment of patients with locally advanced rectal cancer (LARC). The data showed that TNT was associated with improved outcomes compared with standard CRT for these patients.

This study investigated the effectiveness and safety of percutaneous radiofrequency ablation (PRA) in the treatment of colorectal cancer (CRC) liver metastases (LM). Researchers suggested that PRA is a good and safe method for the treatment of these patients. 

The study investigated the impact of adding chemotherapy after surgery to remove liver metastasis on the outcomes of patients with colorectal cancer (CRC). The study reported a significantly longer survival in patients undergoing further chemotherapy.

The aim of this study was to evaluate herbal medicines to treat gastrointestinal (GI) side effects in patients with colorectal cancer (CRC) treated with chemotherapy. The study found that herbal medicines reduced some GI side effects in these patients.

The aim of this study was to evaluate if hepatic arterial infusion chemotherapy (HAIC) could be beneficial for patients with colorectal cancer (CRC) that has spread to the liver (liver metastasis; LM). The study found that HAIC improved the outcome of these patients.

This study evaluated the impact of non-drug therapy on the quality of life (QoL) of patients with colorectal cancer (CRC). The study found that non-drug therapies such as psychological, social, and physical activities were associated with reduced anxiety, depression, and improved QoL.

This study reviewed regional treatment options for patients with colorectal cancer (CRC) and liver metastases (LM; spread to the liver). 

The aim of this study was to evaluate 2 treatment options for patients with colorectal cancer (CRC) that has spread to the liver. The study found that patients who underwent associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) had better outcomes compared to those who had 2-stage hepatectomy (TSH).

This study is searching for participants with advanced solid tumors including colorectal cancer to examine the safety and effectiveness of experimental drug avapritinib (AYVAKIT). The main outcomes to be measured are the response to treatment and side effects. This trial is being conducted in Texas, US.

The aim of this study was to evaluate the impact of adding oxaliplatin (Eloxatin) to the chemotherapy regimen tegafur uracil (UFT)/leucovorin (LV; folinic acid) for patients that had surgery for colorectal cancer (CRC). The study found that the addition of oxaliplatin to UFT/LV improved patient outcomes.