colorectal cancer | Clinical Trial | Added Jul 01, 2019
Searching for patients with unresponsive cancer to test a new treatment
This phase 1/2 trial will investigate the safety of 9-ING-41, for treatment-resistant cancers.
The main outcome will be the number of treatment-related adverse events (TRAEs). This trial is recruiting in the United States.
colorectal cancer | Research | Treatment | 10 pages | source: Clinical Colorectal Cancer | Added Jun 30, 2019
Radiation therapy after surgery improves survival in patients with metastatic rectal cancer
This study investigated the survival outcomes in patients with rectal cancer after surgery with and without radiation therapy (RT). Researchers suggested that RT after surgery is associated with improved outcomes.
colorectal cancer | Clinical Trial | Added Jun 28, 2019
Looking for patients with advanced colorectal cancer to test a new drug
This phase 1 study will investigate the dose range and effectiveness of an experimental drug, XmAb23104, in the treatment of advanced colorectal cancer and other solid tumors.
The main outcome will be the safety and tolerability of XmAb23104. This trial is recruiting in Georgia, Texas, and Virginia, the United States.
colorectal cancer | Clinical Trial | Added Jun 24, 2019
Searching for patients with colorectal cancer to test this new treatment combination
This phase 2 trial is examining the effectiveness and safety of navarixin (MK-7123) in combination with pembrolizumab (Keytruda) in patients with colorectal cancer (CRC). The main outcome to be measured will be the objective response rate (ORR; tumor shrinkage or disappearance).
colorectal cancer | Research | Treatment | 10 pages | source: Annals of Surgical Oncology | Added Jun 20, 2019
A comparison between local and radical surgery in early rectal cancer
This study investigated the effectiveness of local vs radical surgery in patients with rectal cancer. Researchers suggested that local surgery is associated with better outcomes in certain patients with early cancers.
colorectal cancer | Research | 10 pages | source: Cancer Medicine | Added Jun 14, 2019
The risk of pelvic fracture in rectal cancer survivors who had radiotherapy
This study investigated the risk of pelvic fracture (PF) in patients with rectal cancer who received radiation therapy. Researchers suggested that there is an increased risk of PF in these patients.
colorectal cancer | Clinical Trial | Added Jun 02, 2019
Looking for participants with advanced colorectal cancer to test a new targeted treatment with DS-8201a
This phase 2 trial is examining the effectiveness and safety of DS-8201a in the treatment of advanced HER2 positive colorectal cancer. The main outcome to be measured is the tumor response to the treatment and side effects.
colorectal cancer | Research | Treatment | 10 pages | source: BMC cancer | Added May 30, 2019
Cetuximab improves the outcomes of previously untreated patients with metastatic colorectal cancer
This study investigated the effectiveness of first-line treatment with cetuximab (Erbitux) and bevacizumab (Avastin) in advanced colorectal cancer. Researchers suggested that cetuximab is associated with better outcomes when compared to bevacizumab.
colorectal cancer | Clinical Trial | Added May 29, 2019
Looking for patients with advanced BRAF positive colorectal cancer to test an immunotherapy treatment
This trial is examining the effectiveness and safety of encorafenib (Braftovi), binimetinib (Mektovi) and cetuximab (Erbitux) in patients with advanced colorectal cancer. The main outcome to be measured will be tumor response to the treatment.
colorectal cancer | Clinical Trial | Added May 26, 2019
Searching for patients with advanced colorectal cancer to test a new T-cell treatment
This phase 2 trial will investigate the effectiveness of genetically-engineered cell treatment (GECT) in advanced cancer.
The main outcome will be the response to treatment. This trial is recruiting at the National Cancer Institute, Maryland, US.
