This study examined the use of the sulphonylurea glimepiride (Amaryl) in patients with long-standing (10 or more years) type 2 diabetes mellitus.

This study compared the risk of hypoglycemia (dangerously low blood glucose levels) for insulin glargine 300 U/ml (Gla-300; Toujeo) and standard-of-care basal insulin (SOC-BI) at patients with type 2 diabetes (T2D) with risk factors for hypoglycemia. It found that Gla-300 was associated with a lower risk of hypoglycemia than SOC-BI.

This study examined the effectiveness and safety of canagliflozin (Invokana), a glucose (sugar)-lowering therapy, in older adults (aged 55 to 80) with type 2 diabetes.

This study compared the effects of adding insulin glargine treatment  to metformin (Glucophage), glimepiride (Amaryl) or their combination in patients with uncontrolled type 2 diabetes mellitus.

This study compared the effect of two doses of semaglutide (Ozempic), 2.4 mg and 1.0 mg to a placebo, given once weekly subcutaneously (sc; injected under the skin) to adults with overweight or obesity and type 2 diabetes (T2D). The authors concluded that patients treated with 2.4 mg of semaglutide once weekly showed a higher decrease in body weight compared to placebo.

The main objective of this analysis was to determine the benefit of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) compared to insulin treatment in patients with type 2 diabetes who were receiving treatment with oral glucose-lowering medications (OGLM - used to produce insulin in patients who cannot produce enough by themselves).

The authors concluded that slightly better blood sugar control and weight loss was achieved when GLP-1 RAs were added to OGLM compared to insulin treatment. Benefits were also evident in blood pressure, heart rate and hypoglycemia (dangerously low bloog glucose). 

This study looked at how a very-low-calorie ketogenic diet affected people with type 2 diabetes (T2D) and obesity. It found that the ketogenic diet improved weight, blood sugar, and quality of life more than a standard low-calorie diet.

This study investigated whether combination therapy of a statin plus a fibrate, as compared with a statin alone (monotherapy), would diminish the risk of cardiovascular disease in patients with type II diabetes mellitus who were at high risk for cardiovascular disease.

This study aimed to determine the relationship between metformin (Glucophage) use in older adults with diabetes and vitamin B-12 concentrations, and assess whether B-12 supplementation can alter this. Metformin use was shown to be linked to lower B-12 levels, and multivitamin use may be protective against this. 

The current study examined quality of life concerns for patients with type 2 diabetes beginning insulin therapy.