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rheumatoid arthritis | Research | Treatment | 10 pages | source: Clinical and experimental rheumatology | Added Aug 27, 2023

Analyzing the effectiveness and safety of abatacept for rheumatoid arthritis

The study investigated the effectiveness and safety of abatacept (Orencia) for patients with rheumatoid arthritis (RA). The analysis concluded that abatacept gave better results to patients with RA compared to other biologic drugs. 

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rheumatoid arthritis | Research | Treatment | 10 pages | source: Annals of the rheumatic diseases | Added May 26, 2023

Safety and effectiveness of two different doses of daily-administered ABX464 in patients with unresponsive rheumatoid arthritis.

This study investigated the safety and effectiveness of ABX464 (Obefazimod) in patients with active rheumatoid arthritis (RA) with inadequate responses to methotrexate (Trexall) or anti-tumor necrosis factor alpha (anti-TNFα) treatment. The authors concluded that ABX464 was safe and well-tolerated with promising effectiveness in these patients at a daily dose of 50 mg.

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rheumatoid arthritis | Research | Treatment | 10 pages | source: Scientific reports | Added May 24, 2023

Can remission be increased in patients with rheumatoid arthritis by using more biologics and less corticosteroids under real-life conditions?

This study evaluated the 7-year follow-up remission rate and maintenance in patients with rheumatoid arthritis (RA) under real-life conditions and identified factors related to long-term remission. The authors concluded that at 7 years nearly twice as many patients were in remission than at 1 year of follow-up and those patients had mainly received co-prescription with disease-modifying anti-rheumatic drugs (DMARDs).

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rheumatoid arthritis | Research | Treatment | 10 pages | source: Seminars in Arthritis and Rheumatism | Added May 22, 2023

Can low dose prednisolone as an add-on treatment reduce the economic burden for patients with rheumatoid arthritis?

This study evaluated the cost-effectiveness of low-dose prednisolone (Omnipred) at 5 mg daily in the treatment of patients with rheumatoid arthritis (RA) aged 65 years or more. The study found that a low dose of prednisolone was an effective add-on treatment for patients with RA based on similar or lower costs compared to a placebo for over two years.

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rheumatoid arthritis | Research | Treatment | 10 pages | source: Annals of the rheumatic diseases | Added May 20, 2023

Can biologic treatments influence the occurrence of infections in patients with rheumatoid arthritis?

This study compared the occurrence of infections and identified their risk factors in patients with rheumatoid arthritis (RA) that were treated with tofacitinib (Xeljanz) against those given a tumor necrosis factor inhibitor (TNFi). The data showed that serious and non-serious infections were higher in patients that received tofacitinib compared to a TNFi.

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rheumatoid arthritis | Research | 10 pages | source: Scientific reports | Added May 18, 2023

Is osteoporosis more likely to occur in patients with rheumatoid arthritis?

This study investigated the occurrence of osteoporosis (OP) in patients with rheumatoid arthritis (RA). The authors concluded that although significant advancements were made in OP prevention, treatment and diagnosis, a high occurrence was still observed in patients with RA.

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rheumatoid arthritis | Research | Treatment | 10 pages | source: Annals of the rheumatic diseases | Added May 16, 2023

Evaluating the effectiveness of immunomodulators in reducing cardiovascular events in patients with rheumatoid arthritis

The study evaluated the effectiveness of reducing cardiovascular events (CVE) with immunomodulatory (IM) in patients with rheumatoid arthritis (RA). The main finding was that IM showed improvements in vascular inflammation in this group of patients.

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rheumatoid arthritis | Research | Treatment | 10 pages | source: Annals of the rheumatic diseases | Added May 14, 2023

Is the addition of low-dose prednisolone more beneficial than harmful to older patients with rheumatoid arthritis?

This study assessed the effectiveness and safety of daily administered prednisolone (Prelone) at a dose of 5 mg, as an add-on to the standard of care (SOC) in older patients with rheumatoid arthritis (RA). The authors concluded that low-dose prednisolone added to SOC had long-term benefits in these patients with a favorable balance of benefit and harm.

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rheumatoid arthritis | Research | Treatment | 10 pages | source: Frontiers in immunology | Added Sep 17, 2022

Evaluating the effectiveness of different types of acupuncture therapies in the treatment of rheumatoid arthritis.

This analysis compared the effectiveness of different acupuncture therapies combined with disease-modifying anti-rheumatic drugs (DMARDs) in the treatment of rheumatoid arthritis (RA). The data indicated that RA disease activity was most improved by combining electro-acupuncture and DMARDs while fire-needle or moxibustion plus DMARDs were most effective at improving pain and reducing inflammation.

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rheumatoid arthritis | Research | Treatment | 10 pages | source: Arthritis Research & Therapy | Added Apr 03, 2022

Can filgotinib affect patient-reported outcomes and health-related quality of life in patients with rheumatoid arthritis?

This study investigated the effect of filgotinib (Jyseleca) on patient-reported outcomes (PROs) and health-related quality of life (HRQoL) in patients that had active rheumatoid arthritis (RA). The study showed that filgotinib improved PROs in these patients and can be a treatment option for patients with insufficient responses to methotrexate (Otrexup; MTX), biological disease-modifying anti-rheumatic drugs (bDMARDs), and those that are MTX-naive (have never received MTX).

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