This study aims to investigate the long-term effectiveness and safety of the rituximab biosimilar CT-P10 (Truxima) in combination with cyclophosphamide (Cytoxan), vincristine (Oncovin), and prednisone (Deltasone) (CVP) compared with rituximab (Rituxan) for the treatment of advanced-stage follicular lymphoma (FL). The study concluded that the overall safety and long-term effectiveness of CT-P10 are similar to rituximab for the treatment of FL.

This study investigated the effectiveness and safety of panitumumab (Vectibix) when added to maintenance therapy with fluorouracil (Adrucil) and folinic acid (Leucovirin) (FU/FA) in patients with RAS wild-type metastatic colorectal cancer (mCRC). The data showed that maintenance therapy with FU/FA plus panitumumab was safe and effective for these patients.

This study evaluated the effectiveness and safety of different anti-HER2 therapies in combination with chemotherapy for the treatment of patients with metastatic HER2-positive breast cancer (BC). The data showed that THP (taxanes + trastuzumab + pertuzumab) was the best first-line treatment, while Trastuzumab emtansine (T-DM1; Kadcycla) and XHTuC (capecitabine + trastuzumab + tucatinib) were the best second-line treatments for metastatic HER2-positive BC.

This study aimed to review the safety and effectiveness of three chimeric antigen receptor (CAR) T cell therapies, axicabtagene ciloleucel (AXI; Yescarta), tisagenlecleucel (TIS; Kymriah), and lisocabtagene maraleucel (LIS; Breyanzi), for the treatment of blood cancers. 

This study concluded that AXI and TIS showed very good effectiveness but have important toxicity warnings. It was also concluded that LISl showed very good effectiveness and safety in clinical trials only. 

This study aimed to investigate pyrotinib (Irene)-based therapy as a treatment for patients with HER2-positive advanced breast cancer. 

This study concluded that pyrotinib-based therapy was safe and effective in these patients, particularly in those that received 2 or fewer therapies and received capecitabine (Xeloda).  

This study assessed the responses of patients with rheumatoid arthritis (RA) to tofacitinib (Xeljanz), tofacitinib with methotrexate (MTX; Otrexup), and adalimumab (Humira) with MTX. The data showed that some patients did not require combined therapy to achieve higher responses, however, overall, greater responses were achieved with tofacitinib and MTX compared to tofacitinib alone.

This study is aimed to evaluate the risk of infection for patients who are treated with immune checkpoint inhibitors (ICI) for solid tumors. The study concluded that in frail patients, ICI therapy alone is safer compared to chemotherapy (CT).  

In this work, the authors evaluated the effectiveness of safinamide (Xadago) on mood in patients with Parkinson's disease (PD). The study showed that safinamide improved PD patients' mood and emotional wellbeing at 6 months.

This study evaluated the safety and effectiveness of teclistamab (JNJ-64007957) for patients with recurrent or unresponsive multiple myeloma (MM). This study concluded that this treatment was safe and showed promising effectiveness for these patients.

This study compared the therapeutic benefit of topically applied ON101 (Fespixon) cream to an absorbent dressing (Hydrofiber; ConvaTec Ltd) on wound healing in patients with chronic diabetic foot ulcers (DFUs). The authors concluded that the therapeutic effectiveness of ON101 treatment of DFUs was better compared to absorbent dressing.