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infertility & reproductive technologies | Research | 10 pages | source: Archives of Gynecology and Obstetrics | Added Nov 07, 2021

How long should estrogen be supplemented after embryo transfer?

This study evaluated how long estrogen should be used during artificial cycle frozen embryo transfer (FET). It found that stopping estrogen at 6 weeks of pregnancy reduced miscarriages compared to continuing to 12 weeks. Stopping at 6 weeks also led to fewer pregnancy complications.

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breast cancer | Research | Treatment | 10 pages | source: The Lancet. Oncology | Added Nov 07, 2021

Evaluating the long-term benefits and risks of trastuzumab plus chemotherapy in patients with early-stage HER2+ breast cancer.

This study evaluated the long-term benefits and risks of trastuzumab (Herceptin) plus chemotherapy in patients with early-stage HER2-positive (+) breast cancer (BC). The data showed that trastuzumab added to chemotherapy reduced the risk of BC recurrence and death for these patients.

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leukemia | Research | Treatment | 10 pages | source: Haematologica | Added Nov 07, 2021

Evaluating the cardiovascular side effects in patients with chronic lymphocytic leukemia who received acalabrutinib.

This study evaluated the cardiovascular (CV; heart and blood vessels) side effects in patients with chronic lymphocytic leukemia (CLL) who received acalabrutinib (Calquence) treatment. The data showed that the occurrence of CV side effects with acalabrutinib treatment is very low in patients with CLL.

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prostate cancer | Research | 10 pages | source: The Lancet. Oncology | Added Nov 07, 2021

Investigating the side effect profiles of different PD-L1/PD-1 inhibitor-based combination therapies.

This study investigated the side effect profiles of different PD-1/PD-L1 inhibitor-based combination therapies. The data showed that PD-1/PD-L1 inhibitors in combination with chemotherapy were associated with a higher risk of treatment-related side effects than with targeted therapy or immunotherapy combinations.

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diabetes mellitus | Research | Treatment | 10 pages | source: Lancet (London, England) | Added Oct 31, 2021

Effectiveness and safety of tirzepatide compared to insulin degludec in patients with type 2 diabetes.

This study compared the effectiveness and safety of tirzepatide to insulin degludec (Tresiba) in patients with uncontrolled type 2 diabetes (T2D). The data showed that tirzepatide produced better blood glucose control and body weight improvements with reduced risk of hypoglycemia, compared to degludec in these patients.

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diabetes mellitus | Research | 10 pages | source: Diabetes & Metabolism | Added Oct 31, 2021

Improved changes in the eye in patients with type 2 diabetes using dapagliflozin compared to glibenclamide.

This study investigated the change in central retinal thickness (CRT) by optical coherence tomography (OCT) in patients with type 2 diabetes (T2D) after 12 weeks of treatment with dapagliflozin (Farxiga) or glibenclamide (Diabeta). The authors concluded that CRT may improve with short-term use of dapagliflozin compared with glibenclamide treatment.

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melanoma | Research | 10 pages | source: Annals of Surgical Oncology | Added Oct 31, 2021

Evaluating the outcomes of current therapies after surgery for patients with stage III melanoma who did not undergo complete lymph node dissection.

This study evaluated the outcomes of immune and molecular targeted therapies after surgery for patients with stage III melanoma who did not undergo complete lymph node dissection. The data showed that the immune and targeted therapies after surgery were associated with increased survival without metastasis among these patients.

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prostate cancer | Research | Treatment | 10 pages | source: Frontiers in oncology | Added Oct 31, 2021

Evaluating the effectiveness and safety outcomes of second radiation therapy in patients with locally recurrent prostate cancer.

This study investigated the effectiveness and safety of re-irradiation for the treatment of patients with locally recurrent prostate cancer. The data showed that the use of re-irradiation in these patients was associated with good outcomes and low toxicity.

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breast cancer | Research | 10 pages | source: International journal of radiation oncology, biology, physics | Added Oct 31, 2021

Evaluating treatment outcomes of hypofractionated stereotactic radiotherapy in patients with brain metastases.

This study investigated the optimal doses of hypofractionated stereotactic radiation therapy (HSRT) for patients with brain metastases (BM). The data showed that a HSRT dose of 30 Gy or higher delivered in 5 daily fractions was safe and effective in these patients.

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stroke | Research | 10 pages | source: Medicine | Added Oct 25, 2021

Is home-based rehabilitation as effective as a hospital-based programme for stroke patients?

This study compared home-based rehabilitation with hospital-based rehabilitation after a stroke. It found that both programs improved balance and walking in these patients. 

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