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leukemia | Research | 10 pages | source: Blood | Added Mar 20, 2022

Evaluating antibody response rates of patients with chronic lymphocytic leukemia to a third dose of mRNA COVID-19 vaccine

This study aimed to investigate the antibody response to a third mRNA COVID-19 vaccine of patients with chronic lymphocytic leukemia (CLL) who had failed to achieve an antibody response after the standard two-dose vaccination regimen. 

This study concluded that approximately a quarter of patients responded to the third vaccine.  

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diabetes mellitus | Research | 10 pages | source: Diabetes, Obesity and Metabolism | Added Mar 20, 2022

Do patients with diabetes have a different antibody response to COVID-19 vaccines compared to healthy individuals?

This study evaluated the antibody response and side effects associated with COVID-19 vaccines administration in patients with type 1 (T1D) and type 2 diabetes (T2D), people without diabetes. The data showed similar immune responses in patients with and without diabetes after the second COVID-19 vaccine, regardless of glucose control.

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diabetes mellitus | Research | Treatment | 10 pages | source: Diabetes Care | Added Mar 20, 2022

Can high-frequency spinal cord stimulation provide relief to patients with painful diabetic nerve disease?

This study evaluated the long-term impact of 10-kHz spinal cord stimulation (SCS) in patients with painful diabetic neuropathy (PDN; nerve disease) and refractory symptoms. The data supported the use of 10-kHz SCS for important, durable pain relief over 12 months in these patients.

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erectile dysfunction | Research | Treatment | 10 pages | source: Investigative and clinical urology | Added Mar 20, 2022

Investigating the effectiveness and safety of combining low-intensity extracorporeal shock wave therapy with tadalafil and L-arginine for the treatment of erectile dysfunction.

This study investigated the effectiveness and safety of combining low-intensity extracorporeal shock wave therapy (Li-ESWT) with tadalafil (Cialis) and L-arginine for the treatment of patients with mild and moderate erectile dysfunction (ED). The data showed that daily therapy with tadalafil and L-arginine increased the effectiveness and the duration of benefits of Li-ESWT for these patients.

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multiple myeloma | Research | Treatment | 10 pages | source: Blood advances | Added Mar 15, 2022

Evaluating quality of life in patients with relapsed or refractory multiple myeloma treated with idecabtagene vicleucel

This study aimed to investigate the effect of idecabtagene vicleucel (ABECMA; ide-cel) treatment on health-related quality of life (HR-QoL) in patients with relapsed or refractory (r/r) multiple myeloma (MM).  

This study concluded that this treatment improves HR-QoL for these patients.  

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parkinson's disease | Research | Treatment | 10 pages | source: Medicine | Added Feb 27, 2022

Evaluating the effectiveness and safety of ropinirole for the treatment of Parkinson’s disease.

This study evaluated the effectiveness and safety of ropinirole (Requip) for the treatment of patients with Parkinson’s disease (PD). The data showed that ropinirole was effective in improving motor function and daily living of patients with PD but was associated with an increase in side effects.

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breast cancer | Research | Treatment | 10 pages | source: Clinical Cancer Research | Added Feb 25, 2022

Evaluating the effectiveness of trilaciclib given before chemotherapy in patients with metastatic triple-negative breast cancer.

This study evaluated the effectiveness of trilaciclib (Cosela) given before gemcitabine (Gemzar) plus capecitabine (Xeloda) (GC) chemotherapy regimen in patients with metastatic triple-negative breast cancer (mTNBC). The data showed that trilaciclib given before GC chemotherapy regimen was effective and significantly improved overall survival in these patients.

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colorectal cancer | Research | Treatment | 10 pages | source: Frontiers in oncology | Added Feb 13, 2022

Comparing the effectiveness and safety of TAS-102 with or without bevacizumab in patients with metastatic colorectal cancer.

This study evaluated the effectiveness and safety of bevacizumab (Avastin) plus TAS-102 (Lonsurf; trifluridine-tipiracil) versus TAS-102 alone for the treatment of patients with metastatic colorectal cancer (mCRC). The data showed that bevacizumab combined with TAS-102 was effective with manageable side effects in improving the outcomes of these patients.

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multiple myeloma | Research | Treatment | 10 pages | source: British Journal of Cancer | Added Feb 13, 2022

Effects of combined treatment with selinexor, carfilzomib and dexamethasone once a week in patients with relapsed/refractory multiple myeloma

This study evaluated the safety and effectiveness of selinexor (Xpovio) in combination with carfilzomib (Kyprolis) and dexamethasone (Decadron) (XKd) in patients with relapsed/refractory (r/r) multiple myeloma (MM) that still responded to carfilzomib. The data showed that weekly administered XKd was highly effective and well-tolerated in these patients.

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diabetes mellitus | Research | Treatment | 10 pages | source: Diabetes Research and Clinical Practice | Added Feb 13, 2022

Comparing chiglitazar and sitagliptin effectiveness on glucose variations, insulin resistance and inflammation levels in patients with type 2 diabetes.

This study compared the effectiveness of chiglitazar (Bilessglu) and sitagliptin (Januvia) on glycemic (blood glucose) variations, insulin resistance, and inflammation levels in patients with type 2 diabetes (T2D). The data showed that chiglitazar treatment was more effective at improving insulin resistance and inflammation compared with sitagliptin in these patients.

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