This study assessed the effects of canagliflozin (Invokana) therapy on body composition, glucose control, insulin resistance, and systemic (whole body) inflammation in patients with newly-diagnosed type 2 diabetes (T2D) compared to metformin (Glucophage). The data showed that canagliflozin therapy reduced visceral fat tissue, and improved blood glucose, insulin resistance, and systemic inflammation in these patients.

This study determined the effect of varying carbohydrate and saturated fat dietary contents on cardiovascular disease (CVD) risk factors during weight-loss maintenance. The authors concluded that restriction of carbohydrates provided improved insulin resistance on lipoprotein metabolism, without unwanted side effects on low-density lipoprotein (LDL) cholesterol or inflammation.

This study evaluated the effectiveness and safety of etoposide (Etopophos) combined with cytarabine (Cytosar-U) plus granulocyte colony-stimulating factor (G-CSF, Neupogen) in patients with multiple myeloma (MM) for stem cell mobilization. The data showed that etoposide combined with cytarabine plus G-CSF was safe and effective for the collection of stem cells for autologous stem cell transplantation (ASCT) in these patients.

The study aimed to investigate if immunocompromised patients with blood cancers benefit from COVID-19 vaccination. This study concluded that these patients should not be excluded from COVID-19 vaccination. 

This study compared the effectiveness of common immuno-chemotherapy (ICT) treatments for advanced follicular lymphoma (FL) for front-line therapy. The study showed that obinutuzumab (Gazyva; G) combined with bendamustine (Treanda; Benda) (G-Benda-G regimen) had the best survival without cancer worsening in patients with advanced FL. 

This study aimed to investigate infusion reactions and the effectiveness of the combination of obinutuzumab (Gazyva) and chlorambucil (Leukeran) in patients with chronic lymphocytic leukemia (CLL). 

This study concluded that first dose infusion reactions with obinutuzumab can be reduced by using chlorambucil first and by using a very slow initial obinutuzumab dose. 

This study assessed the link between metformin (Glucophage) use in hospitalized and non-hospitalized patients with diabetes and different outcomes due to coronavirus disease 2019 (COVID-19). The study showed that metformin use was associated with a protective effect in COVID-19 outcomes in patients with type 2 diabetes (T2D).

This study analyzed the impact of cognitive-motor dual-task training (CMDT) on patients with chronic stroke. The authors concluded that CMDT had beneficial effects on balance ability, gait, and upper limb function in patients with chronic stroke.

This study evaluated the effectiveness and safety of an all-oral combination of ixazomib (Ninlaro), lenalidomide (Revlimid), and dexamethasone (Decadron) in transplant-eligible patients with newly diagnosed multiple myeloma (MM). The data showed that this combination was effective with manageable side effects in these patients.

This study reported the long-term effectiveness and safety of adding carboplatin (Paraplatin) with or without veliparib (ABT-888) to standard chemotherapy given before surgery (neoadjuvant chemotherapy; NACT) in patients with early-stage triple-negative breast cancer (TNBC). The data showed that the addition of carboplatin to standard NACT was associated with a long-term survival benefit without increasing the risk of second cancers in these patients.