In a nutshell The study wanted to find out if taking the drug metformin (Glucophage) prevents insulin resistance and issues with the womb caused by tamoxifen (Novaldex) in women with breast cancer. The study found that metformin was able to prevent changes in the womb caused by tamoxifen, and also resulted in weight loss and lower...Read More
Type(s) of hormonal therapy-Anti-estrogen drugs-Tamoxifen (Nolvadex) Posts on Medivizor
In a nutshell This study looked at the risk factors and protective factors surrounding non-alcoholic fatty liver disease in relation to tamoxifen (Novaldex) therapy for women with breast cancer. The authors found that a high BMI was a risk factor for tamoxifen related fatty liver disease, while exercise was a protective factor. Some background...Read More
In a nutshell The authors aimed to determine the risks of cancer recurrence (the cancer returns) between the time of hormone or endocrine therapy and the 10 years following. Some background Endocrine therapy is used as treatment against particular cancers that may grow in response to hormones natural to our body. This includes hormone...Read More
In a nutshell The authors aimed to assess the prognostic (treatment outlook) factors associated with breast cancer in post-menopausal women with specific tumor characteristics. Some background Lymph nodes are tiny bean shaped organs and are often the first site to which cancer will spread. This is known as lymph node involvement. Adjuvant...Read More
In a nutshell The authors aimed to determine if there was a link between patient age, tumor type and the spread of cancer. Some background Breast cancer metastasis is the spread of the cancer to other parts of the body; following original cancer of the breast. Age at original diagnosis and the area affected by the tumor are just two of the...Read More
In a nutshell This article looked at the risks of developing uterine cancer in women who have survived breast cancer. Some background Uterine cancer (cancer of the uterus, or 'womb') is the most common gynaecologic tumor in women (tumors relating to the female reproductive organs). Certain factors associated with breast cancer can become...Read More
In a nutshell The aim of this study was to investigate the relationship between survival outcomes and specific adverse events (AEs) in patients after menopause (postmenopausal) with breast cancer treated with hormone therapy. Some background Most breast cancers grow in response to estrogen, the main female sex hormone. Therefore, hormone therapy...Read More
Can breast tissue density change at mammography predict survival in patients with breast cancer treated with tamoxifen?
In a nutshell This article evaluated whether a reduction in tissue density at mammography after tamoxifen treatment can predict survival in breast cancer patients. Some background Mammography uses x-rays to look at the breasts for signs of cancer. This diagnostic method is generally used for women over the age of 50. Younger patients usually have...Read More
Does radiation therapy improve survival in early stage breast cancer patients treated with lumpectomy and tamoxifen?
In a nutshell This study evaluated whether there is any benefit from radiation therapy (RT) in women over the age of 70 with early stage breast cancer treated with lumpectomy (surgical removal of the cancerous lump) and tamoxifen. Some background Breast cancer in older patients is often fueled by estrogen, a female sex hormone. These cancer...Read More
In a nutshell The aim of this article was to discuss the way in which the latest results on cancer DNA research apply to early-stage breast cancer. Genome analysis is highly likely to play a growing role in the future but more clinical trials are needed. Some background Breast cancer is a disease with multiple symptoms and consequences that are...Read More
In a nutshell This study compared the benefits of chemotherapy according to hormone receptor status. The main findings were: In cancers without hormone receptors, the benefits of adding chemotherapy were significant; In cancers with hormone receptors, chemotherapy only offered modest improvement. Some background Some...Read More
In a nutshell This article reports long-term results of the UK/ANZ DCIS (“UK/Australia and New Zealand Ductal Carcinoma in Situ”) trial. This study investigated the use of radiation treatment and Tamoxifen treatments in DCIS. Some background Ductal carcinoma in situ (DCIS) is the most common type of non-invasive breast cancer....Read More