In a nutshell This study evaluated the effects of olaparib (Lynparza) on pain and the health-related quality of life (HR-QoL) in patients with metastatic castration-resistant prostate cancer (mCRPC) with mutations (genetic abnormalities) in DNA repair genes. The data showed that treatment with olaparib was associated with a reduction in pain and...
Read MoreType(s) of hormonal therapy-Anti-androgens Posts on Medivizor
Comparing two hormone therapy drugs in men with advanced, non-metastatic prostate cancer
In a nutshell This study aimed to compare two hormone therapies, gonadotropin-releasing hormone (GnRH) agonists and anti-androgen therapy (AA) in men with advanced, non-metastatic prostate cancer. This study found that the two therapies have similar outcomes, but by starting with AA treatment may reduce side effects associated with GnRH...
Read MoreLooking for patients with prostate cancer who have had a rise in PSA after prostate removal surgery
In a nutshell This trial is examining the effectiveness of different hormone therapy regimes for patients whose prostate specific antigen (PSA; a protein elevated in prostate cancer) levels rise after prostate removing surgery. The main outcome to be measured will be the change in PSA levels. The details The best standard treatment...
Read MoreSearching for men undergoing androgen deprivation therapy to participate in diet and exercise program
In a nutshell This trial is examining the effectiveness of diet and exercise during ADT treatment for men with prostate cancer. The main outcome to be measured will be the change in body mass index (BMI, a measure of body fat that takes height and weight into account). This study is being conducted in Los Angeles and Kansas City,...
Read MoreEnzalutamide – a new treatment for improving prostate cancer outcomes
In a nutshell The authors interpreted the results of a phase III trial on the use of enzalutamide (Xtandi) in treating patients with metastatic (cancer that has spread) hormone-resistant (castration-resistant) prostate cancer. Some background Hormone therapy is a common treatment used in prostate cancer. It targets the male sex hormones...
Read MoreFibrinogen – a new predictor in prostate cancer
In a nutshell The authors evaluated whether fibrinogen could be used to determine cancer survival in prostate cancer. Some background Fibrinogen is a very important protein that clots blood inside the body. It has previously been used to determine the metastatic potential (likelihood that the cancer cells will spread) of lung cancers and...
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