In a nutshell This study investigated the change in outcomes over 10-years in patients with stage 3 colon cancer who received FOLFOX chemotherapy. Researchers suggested that this treatment improved the outcomes of these patients. Some background Colorectal cancer is the third most common cancer diagnosed in both men and women in the US. The...
Read MoreType(s) of colorectal cancer (CRC)?-Adenocarcinoma of the colon Posts on Medivizor
Does laparoscopic surgery decrease complications after colorectal cancer surgery?
In a nutshell This study investigated if laparoscopic surgery (LS) is associated with fewer complications in colorectal cancer compared to classic, open surgery. Researchers suggested that LS decreases the odds of having a complication after colorectal cancer surgery. Some background Colorectal cancer is one of the most common cancer...
Read MoreAre intense follow-up programs beneficial for patients with colorectal cancer?
In a nutshell This study reviewed the effect of follow-up programs on the survival of patients with colorectal cancer. Researchers suggested that intense follow-up programs do not improve the survival of these patients. Some background Colorectal cancer is a commonly diagnosed cancer in the US. Two in three patients will present with the possibly...
Read MoreRadiation therapy after surgery improves survival of patients with advanced colon cancer
In a nutshell This study investigated the effectiveness of radiation therapy (RT) after surgery in patients with T4 (cancer that has grown outside of the colon outer layer and invades the surrounding tissues) colon cancer. Researchers suggested that RT improved overall survival in these patients. Some background Colorectal cancer is the third...
Read MoreTreatment dose optimisation in patients with advanced colorectal cancer treated with regorafenib
In a nutshell This study investigated the effectiveness and safety of increasing doses of regorafenib (Stivarga) doses in patients with advanced colorectal cancer. Researchers suggested that this method with increasing doses should be used to assess the optimal dose for each patient. Some background Colorectal cancer is the third most common cancer...
Read MoreLooking for participants to test a vaccine for the treatment of advanced colorectal cancer
In a nutshell This phase 1b trial is examining the effectiveness and safety of a vaccine treatment, ATP128, in the treatment of advanced colorectal cancer. The main outcome to be measured is the tumor response to the treatment and treatment toxicity. This trial is being conducted in Arizona and California, US. The details Colorectal cancer is the...
Read MoreLaparoscopic surgery is associated with improved quality of life in patients with colorectal cancer
In a nutshell This study investigated the quality of life of patients with colorectal cancer treated with surgery. Researchers suggested that laparoscopic surgery (LS) is associated with an improved quality of life. Some background The standard treatment for colorectal cancer is open surgery or LS. LS consists in inserting a tube with a camera through...
Read MoreAbdominal symptoms affecting the quality of life after surgery for colon cancer
In a nutshell This study compared abdominal (stomach/intestinal) symptoms (AS) between patients with colorectal cancer after colon surgery and after rectal surgery. Researchers suggested that complaints between both groups of patients are similar. Some background Colorectal cancer survivors often have long-term side effects from the cancer and its...
Read MoreTumor budding as a prognostic factor for treatment outcomes in patients with stage 2 colon cancer
In a nutshell This study investigated the role of tumor budding (TB) in predicting the best treatment for stage 2 colon cancer. Researchers suggested that TB could improve the effect of chemotherapy after surgery in these patients. Some background Stage 2 colorectal cancer accounts for one-third of patients who undergo curative surgery. Prognostic...
Read MoreLooking for participants with advanced colorectal cancer to test a new immunotherapy
In a nutshell This phase 1 trial is examining the effectiveness of personalized tumor antigens (PTA) in the treatment of different advanced tumors. The main outcomes to be measured will be side effects and disease control. This study is being conducted in Arizona, California, Louisiana and New Jersey, US. The details While the tumor cells are growing,...
Read MoreLooking for participants with metastatic melanoma to test a new immunotherapy
In a nutshell This phase 1 trial is examining the effectiveness of personalized tumor antigens (PTA) in the treatment of different advanced tumors. The main outcomes to be measured will be side effects and disease control. This study is being conducted in Arizona, California, Louisiana and New Jersey, US. The details While the tumor cells are growing,...
Read MoreLooking for patients with BRAF positive inoperable colorectal cancer to test a new treatment combination
In a nutshell This phase 1/2 trial is examining the best dose and side effects of a combined treatment with encorafenib (Braftovi), cetuximab (Erbitux) and nivolumab (Opdivo). The main outcome to be measured will be the tumor response to the treatment. This trial is being conducted in Texas, US. The details Colorectal cancer is one of the leading...
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