Type(s) of colorectal cancer (CRC)-Adenocarcinoma of the colon Posts on Medivizor
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Type(s) of colorectal cancer (CRC)-Adenocarcinoma of the colon Posts on Medivizor

Treatment dose optimisation in patients with advanced colorectal cancer treated with regorafenib

Posted by on Sep 25, 2019 in Colorectal cancer | 0 comments

In a nutshell This study investigated the effectiveness and safety of increasing doses of regorafenib (Stivarga) doses in patients with advanced colorectal cancer. Researchers suggested that this method with increasing doses should be used to assess the optimal dose for each patient. Some background Colorectal cancer is the third most common cancer...

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Looking for participants to test a vaccine for the treatment of advanced colorectal cancer

Posted by on Sep 10, 2019 in Colorectal cancer | 0 comments

In a nutshell This phase 1b trial is examining the effectiveness and safety of a vaccine treatment, ATP128, in the treatment of advanced colorectal cancer. The main outcome to be measured is the tumor response to the treatment and treatment toxicity. This trial is being conducted in Arizona and California, US. The details Colorectal cancer is the...

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The effects of maintenance vs intermittent therapy in the treatment of advanced colorectal cancer

Posted by on Sep 4, 2019 in Colorectal cancer | 0 comments

In a nutshell This study investigated the effects of maintenance therapy (MT) compared to intermittent therapy (IT) for patients with metastatic (spread to other parts of the body) colorectal cancer. Researchers suggested that MT might improve the treatment of these patients. Some background Colorectal cancer is the second most common cancer...

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Laparoscopic surgery is associated with improved quality of life in patients with colorectal cancer

Posted by on Aug 30, 2019 in Colorectal cancer | 0 comments

In a nutshell This study investigated the quality of life of patients with colorectal cancer treated with surgery. Researchers suggested that laparoscopic surgery (LS) is associated with an improved quality of life. Some background The standard treatment for colorectal cancer is open surgery or LS. LS consists in inserting a tube with a camera through...

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Abdominal symptoms affecting the quality of life after surgery for colon cancer

Posted by on Aug 28, 2019 in Colorectal cancer | 0 comments

In a nutshell This study compared abdominal (stomach/intestinal) symptoms (AS) between patients with colorectal cancer after colon surgery and after rectal surgery. Researchers suggested that complaints between both groups of patients are similar. Some background Colorectal cancer survivors often have long-term side effects from the cancer and its...

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Tumor budding as a prognostic factor for treatment outcomes in patients with stage 2 colon cancer

Posted by on Aug 21, 2019 in Colorectal cancer | 0 comments

In a nutshell This study investigated the role of tumor budding (TB) in predicting the best treatment for stage 2 colon cancer. Researchers suggested that TB could improve the effect of chemotherapy after surgery in these patients. Some background Stage 2 colorectal cancer accounts for one-third of patients who undergo curative surgery. Prognostic...

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Looking for participants with advanced colorectal cancer to test a new immunotherapy

Posted by on Aug 14, 2019 in Colorectal cancer | 0 comments

In a nutshell This phase 1 trial is examining the effectiveness of personalized tumor antigens (PTA) in the treatment of different advanced tumors. The main outcomes to be measured will be side effects and disease control. This study is being conducted in Arizona, California, Louisiana and New Jersey, US. The details While the tumor cells are growing,...

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Looking for participants with metastatic melanoma to test a new immunotherapy

Posted by on Aug 14, 2019 in Melanoma | 0 comments

In a nutshell This phase 1 trial is examining the effectiveness of personalized tumor antigens (PTA) in the treatment of different advanced tumors. The main outcomes to be measured will be side effects and disease control. This study is being conducted in Arizona, California, Louisiana and New Jersey, US. The details While the tumor cells are growing,...

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Looking for patients with BRAF positive inoperable colorectal cancer to test a new treatment combination

Posted by on Aug 14, 2019 in Colorectal cancer | 0 comments

In a nutshell This phase 1/2 trial is examining the best dose and side effects of a combined treatment with encorafenib (Braftovi), cetuximab (Erbitux) and nivolumab (Opdivo). The main outcome to be measured will be the tumor response to the treatment. This trial is being conducted in Texas, US. The details Colorectal cancer is one of the leading...

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Is there a best duration of post-surgery chemotherapy in patients with colon cancer?

Posted by on Jul 28, 2019 in Colorectal cancer | 0 comments

In a nutshell This study compared a 3-month with a 6-month chemotherapy treatment after colon cancer surgery. Researchers suggested that the duration of the treatment should be chosen according to the patient condition. Some background Colorectal cancer is one of the most common cancers worldwide. Stage 2 and 3 colon cancer are common and curable...

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Searching for patients to try a new therapy for advanced solid tumors.

Posted by on Jul 24, 2019 in Colorectal cancer | 0 comments

In a nutshell This study is searching for participants with advanced solid tumors to try a new treatment called repotrectinib (TPX-0005). The main outcomes that will be measured include side effects, the most effective dose and response. This trial is recruiting in the United States and Korea. The details Patients with different genetic mutations...

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Liver surgery is a safe treatment for patients with BRAF-positive colorectal cancer liver metastasis

Posted by on Jul 8, 2019 in Colorectal cancer | 0 comments

In a nutshell This study investigated the outcomes of patients with BRAF-positive colorectal cancer liver-metastasis (CRLM; spread to the liver) undergoing surgery. Researchers suggested that surgery is associated with improved outcomes for these patients. Some background Colorectal cancer is one of the most common cancers in the US. Around 25% of...

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