In a nutshell This study evaluated the effectiveness and safety of oral paclitaxel (Taxol) plus encequidar (HM 30181) versus intravenous (IV) paclitaxel in patients with metastatic breast cancer (BC). This study concluded that oral paclitaxel plus encequidar was more effective than IV paclitaxel with manageable side effects in these...
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Zoledronic acid as an option for HER2-negative breast cancer
In a nutshell This study aimed to investigate zoledronic acid in combination with chemotherapy as a treatment for HER2-negative breast cancer. This study concluded that the addition of zoledronic acid to chemotherapy has potential benefits for certain breast cancer patients. Some background HER2-negative breast cancer (BC) differs from...
Read MoreLifestyle factors affecting chemotherapy-induced peripheral neuropathy
In a nutshell This study investigated the effects of specific lifestyle factors in the incidence and severity of chemotherapy-induced peripheral neuropathy (CIPN) in breast cancer patients. This study found that obesity, antioxidant supplements and physical activity were associated with CIPN. Some background CIPN, or damage to the...
Read MoreEribulin – a treatment for metastatic breast cancer
In a nutshell This study investigated the safety and effectiveness of the drug eribulin (Halaven) for the treatment of patients with metastatic breast cancer and resistance to taxane therapies. The study concluded that eribulin was effective and well tolerated in patients with metastatic breast cancer. Some background Taxanes are a type of...
Read MoreAdvanced breast cancer; improving chemotherapy treatment
In a nutshell The authors aimed to evaluate a series of treatments used for advanced breast cancer; this was a review of chemotherapy drugs such as paclitaxel (Taxol), doxetaxel (Taxotere) and nab-paclitaxel (Abraxane). Some background Taxanes are a group of chemotherapy drugs used commonly in locally advanced (cancer has spread into nearby...
Read MoreTraditional Chinese medicine; the effects on breast cancer survival
In a nutshell The authors aimed to assess the effectiveness of traditional Chinese medicine used with conventional breast cancer treatments on breast cancer survival. Some background Traditional Chinese medicine is an alternative therapy that can complement breast cancer treatments. This generally includes various forms of herbal medicine,...
Read MoreComparison between different chemotherapy regimens for early breast cancer
In a nutshell The present study compared the long-term efficacy and safety of different adjuvant chemotherapy regimens for breast cancer. Main results: chemotherapy clearly provides survival benefits; the higher the dosage, the higher the survival rates, despite more toxicity. Some background Many women with early stage breast cancer receive...
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