In a nutshell The study investigated whether chemotherapy after surgery with or without docetaxel (Taxotere) has different outcomes in patients with different body mass indexes (BMI; a measurement of body weight in relation to height) and early breast cancer (BC). The main finding was that patients responded differently to docetaxel based on...
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Combination chemotherapy and radiation therapy in locally advanced breast cancer
In a nutshell This study aimed to find out if radiation added to standard chemotherapy could increase the response to treatment for locally advanced breast cancer. This study found that neoadjuvant radiation added to chemotherapy improved response but not overall survival. Some background Chemotherapy is a treatment option for...
Read MoreCombined chemotherapy in patients with metastatic breast cancer
In a nutshell This study examined the effects of a combination of two treatments, low-dose capecitabine (Xeloda) and docetaxel (Taxotere), versus docetaxel alone in patients with metastatic, HER2-negative breast cancer. The study concluded that combination treatment improved time to disease progression. Some background...
Read MoreLifestyle factors affecting chemotherapy-induced peripheral neuropathy
In a nutshell This study investigated the effects of specific lifestyle factors in the incidence and severity of chemotherapy-induced peripheral neuropathy (CIPN) in breast cancer patients. This study found that obesity, antioxidant supplements and physical activity were associated with CIPN. Some background CIPN, or damage to the...
Read MoreEribulin – a treatment for metastatic breast cancer
In a nutshell This study investigated the safety and effectiveness of the drug eribulin (Halaven) for the treatment of patients with metastatic breast cancer and resistance to taxane therapies. The study concluded that eribulin was effective and well tolerated in patients with metastatic breast cancer. Some background Taxanes are a type of...
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