In a nutshell This study examined whether the timing of adjuvant chemotherapy affects survival among women with breast cancer. Some background Surgical resection to remove all cancerous tissue is the standard of care for the treatment of breast cancer. After surgery, many patients also undergo adjuvant treatments (additional therapy following...
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In a nutshell This study evaluated the efficacy and safety of accelerated partial breast irradiation (APBI) using the MammoSite device for the treatment of patients after breast conserving surgery. Some background After breast conserving surgery (BCS; surgical removal of the tumor and surrounding tissue without removal of the entire breast),...
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In a nutshell This study evaluated whether the Body Mass Index (BMI) influences the quality of life of breast cancer patients treated with radiotherapy. Some background The Body Mass Index (BMI) is a weight to height ratio calculated by dividing a person’s weight in kilograms to their square of height in meters. A normal BMI ranges...
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In a nutshell This study compared the effectiveness of three adjuvant chemotherapy regimens used in the treatment of node positive breast cancer. Some background Adjuvant chemotherapy refers to chemotherapy given in addition to surgery in an attempt to destroy any remaining cancer cells and to prevent cancer recurrence. Adjuvant chemotherapy is...
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In a nutshell This study examined the benefits of nanoparticle albumin-bound paclitaxel in combination with bevacizumab as first-line treatment (the first treatment of choice) for metastatic breast cancer patients. Some background Paclitaxel is one of several chemotherapy drugs used to treat cancer. However, treatment is often associated with...
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In a nutshell In this study, researchers examined the effect of epoetin alfa (Epogen; Procrit) on anemia (low count of red blood cells) caused by chemotherapy in breast cancer patients. Some background Breast cancer is caused by a defect that makes some breast cancer cells grow and multiply rapidly. One of the treatment options for patients with...
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A total of 173 patients with metastatic (a cancer that has spread to other organs) TNBC were involved in the study. 115 patients were assigned to receive cisplatin and cetuximab together, while 58 patients received cisplatin alone. 20% of the patients treated with cisplatin plus cetuximab showed some response to treatment, compared to only...
Read MoreIn a nutshell In this study researchers examined the effect of a specific chemotherapy combination on disease-free survival in patients with node negative breast cancer. FAC treatment was compared to FAC treatment plus paclitaxel (FACwP). Some background A combination of the drugs fluorouracil (efudex), doxorubicin (doxil), and cyclophosphamide...
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In a nutshell This trial compared treatment with trastuzumab (herceptin) in combination with docetaxel, to a new combination drug called trastuzumab emtansine. Some background Some breast cancer cells have certain receptors on their surface that respond to growth inducing molecules. These cancers are referred to as being human epidermal growth...
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