Type(s) of breast cancer-Ductal carcinoma-Invasive ductal carcinoma Page 2 Posts on Medivizor
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Type(s) of breast cancer-Ductal carcinoma-Invasive ductal carcinoma Posts on Medivizor

Cetuximab and cisplatin in the treatment of metastatic triple negative breast cancer

Posted by on Jul 15, 2013 in Breast cancer | 0 comments

A total of 173 patients with metastatic (a cancer that has spread to other organs) TNBC were involved in the study. 115 patients were assigned to receive cisplatin and cetuximab together, while 58 patients received cisplatin alone. 20% of the patients treated with cisplatin plus cetuximab showed some response to treatment, compared to only...

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Does Oncotype DX testing reduce the use of chemotherapy in patients with estrogen receptor positive breast cancer?

Posted by on Jul 9, 2013 in Breast cancer | 0 comments

In a nutshell In this study, researchers evaluated whether a genetic test called Oncotype DX, reduced the use of chemotherapy treatment for patients with node-positive and estrogen-receptor positive breast cancer. Some background Some breast cancers grow in response to estrogen, the main female sex hormone, via their receptor (a protein found on...

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Comparing survival rates in women diagnosed with cancer in one or both breasts

Posted by on Jul 5, 2013 in Breast cancer | 0 comments

In a nutshell This study compared survival rates of patients who developed cancer in both breasts (called contralateral breast cancer or CBC) and patients who had cancer in one breast (unilateral breast cancer or UBC). Some background Breast cancer is the most common cancer among women. Breast cancer survivors are 3.5 times more likely to develop...

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Phase 3 clinical trial evaluating the safety and efficacy of adding pertuzumab to trastuzumab and docetaxel therapy in patients with HER2+ metastatic breast cancer

Posted by on Jun 9, 2013 in Breast cancer | 0 comments

In a nutshell This phase 3 clinical trial evaluated the safety and efficacy of adding pertuzumab to trastuzumab and docetaxel for the treatment of patients with HER2+ metastatic breast cancer (mBC). Some background Some breast cancer cells have on their surface some proteins called human epidermal growth factor receptor 2 (HER2) that help...

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Does breast cancer type and hormone status influence the efficacy of hormone therapy in breast cancer patients?

Posted by on Jun 1, 2013 in Breast cancer | 0 comments

In a nutshell This study evaluated the efficacy of hormone therapy in patients with two types of breast cancer, invasive ductal breast carcinomas (IDC) and invasive lobular breast carcinomas (ILC) based on hormonal status.  Some background Breasts are made up of lobules (milk-producing glands) and ducts (tubes that carry the milk to the...

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Phase 3 clinical trial evaluating the safety and efficacy of adding docetaxel to doxorubicin and cyclophosphamide chemotherapy in node positive breast cancer patients

Posted by on May 30, 2013 in Breast cancer | 0 comments

In a nutshell In this phase 3 clinical trial, two types of adjuvant (a treatment given in addition to a main treatment) chemotherapy regimens were compared in women with node positive breast cancer after surgery to remove the cancer. These were the combination of docetaxel (Taxotere), doxorubicin and cyclophosphamide (TDC) or the combination of...

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Does breast cancer subtype influence the risk of recurrence in breast cancer patients?

Posted by on May 28, 2013 in Breast cancer | 0 comments

In a nutshell This review evaluated the association between breast cancer subtypes and the risk of recurrence (return of the cancer) in breast cancer patients.  Some background Breast cancers (BC) can be classified based on the presence on their surface of some proteins called receptors which can influence how these cancers work. Most BC...

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The use of genetic testing for selecting the best treatment for early-stage breast cancer

Posted by on Apr 23, 2013 in Breast cancer | 0 comments

In a nutshell The aim of this article was to discuss the way in which the latest results on cancer DNA research apply to early-stage breast cancer. Genome analysis is highly likely to play a growing role in the future but more clinical trials are needed. Some background Breast cancer is a disease with multiple symptoms and consequences that are...

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Assessment of lymph node involvement in recurrent breast cancer: results of a nationwide registration study

Posted by on Apr 7, 2013 in Breast cancer | 0 comments

In a nutshell In patients with recurrent breast cancer, knowledge of regional lymph node involvement serves as an important guide for disease prognosis and treatment decisions. The study presented here investigates the feasibility of “repeat sentinel node biopsy” (SNB) as a prognostic indicator instead of the more invasive “axillary...

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Repeat conservative breast surgery for patients with breast cancer recurring in the same breast

Posted by on Mar 14, 2013 in Breast cancer | 0 comments

In a nutshell The aim of this study was to establish the criteria for selecting the best candidates to receive a second breast–conserving surgery (BCS) after ipsilateral breast tumor recurrence (IBTR- reappearance of a breast tumor on the same side).   Some background Some patients with primary breast cancer who receive BCS and...

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Local recurrence rates of breast cancer if treated with chemotherapy before or after surgery

Posted by on Mar 14, 2013 in Breast cancer | 0 comments

In a nutshell This paper investigates which approach provides longer recurrence free survival time after breast conserving surgery – pre- or post-operative chemotherapy.  Some background Breast conserving surgery (lumpectomy) or BCS is surgery to remove the cancer and a section of healthy tissue around it. Women who choose this...

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