In a nutshell This study investigated the effectiveness and safety of a tumor bed (where the tumor was present) boost after whole breast irradiation (WBI) following breast-conserving surgery (BCS) in patients with non-low-risk ductal carcinoma in situ (DCIS). The data showed that a tumor bed boost after WBI following BCS reduced local recurrence (return...
Read MoreType(s) of breast cancer-Ductal carcinoma-Ductal carcinoma in situ Posts on Medivizor
Ductal carcinoma in situ and surgery: What type is best?
In a nutshell This study aimed to identify rates of contralateral breast cancer (CBC) and ipsilateral breast tumor recurrence (IBTR) after breast conserving surgery (BCS). This study found that rates of CBC were low and the risk of CBC was not associated with age, family history, presentation, year of surgery or radiation. Some background...
Read MoreWho should receive radiotherapy after breast-conserving surgery for ductal carcinoma in situ?
In a nutshell This study investigated the rate of loco-regional recurrence (LRR) when breast-conserving surgery (BSC) was not followed by radiotherapy. This study concluded that the rate of LRR was low in patients who did not undergo radiation after BCS, but that age and margin width were risk factors for LRR. Some background BCS is a surgery...
Read MoreTreatment options for ductal carcinoma in situ and the risk of invasive breast cancer
In a nutshell The authors aimed to determine the effect of different treatments on the risk of developing invasive breast cancer (IBC) in women diagnosed with ductal carcinoma in situ (DCIS). The authors concluded that there was an interaction between age and follow-up period on IBC risk and that the benefit of radiation seemed to be smaller among...
Read MoreIs the removal of lymph nodes always necessary in ductal carcinoma in situ?
In a nutshell The authors aimed to evaluate the point at which the removal of a node in patients with breast cancer was necessary. Some background Sentinel lymph nodes (SLN) are first nodes (small bean-shaped organs located close to blood vessels) to which cancer can spread. Cancer-positive SLN’s have become increasingly prevalent in ductal...
Read MoreIs it better to have radiotherapy or not for ductal carcinoma in situ?
In a nutshell This paper studied whether observation or radiotherapy after breast-conserving surgery (surgery to remove part of breast) was better for patients with ductal carcinoma in situ. Some background Ductal carcinoma in situ describes cancer that starts in the milk ducts of the breast, and that has not spread to surrounding breast...
Read MoreTreatment choice affects recurrence rates for ductal carcinoma in situ patients
In a nutshell The study examined the recurrence rates and disease-free survival times associated with different treatments used for ductal carcinoma in situ. Some background In women with ductal carcinoma in situ, an early form of breast cancer, cancer cells are found only in the milk ducts of the breast. The increased use of screening mammograms...
Read MoreEvaluating the effects of tamoxifen after surgery in women with ductal carcinoma in situ
In a nutshell This review analyzed the effect of tamoxifen (Nolvadex) on survival and risk of recurrence (return of the cancer) in patients with ductal carcinoma in situ (DCIS). Some background DCIS is a type of early-stage breast cancer. The cancer begins in the milk ducts of the breast breast and stays in its original place (in situ). This...
Read MoreWhich adjuvant treatment for DCIS best prevents recurrence at 12-year follow-up?
In a nutshell This article reports long-term results of the UK/ANZ DCIS (“UK/Australia and New Zealand Ductal Carcinoma in Situ”) trial. This study investigated the use of radiation treatment and Tamoxifen treatments in DCIS. Some background Ductal carcinoma in situ (DCIS) is the most common type of non-invasive breast cancer....
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