In a nutshell The study evaluated treatment outcomes reported by patients with metastatic non-small-cell lung cancer (mNSCLC) who were treated by pembrolizumab (Keytruda) and pemetrexed (Alimta) and platinum chemotherapy. The authors found that adding pembrolizumab to pemetrexed-platinum chemotherapy improved health-related quality of life (HRQOL)...
Read MoreType of lung cancer-Non-small cell lung carcinoma (NSCLC)-Adenocarcinoma Posts on Medivizor
Evaluating osimertinib for elderly patients over age 80 with advanced NSCLC
In a nutshell This study evaluated the effectiveness of osimertinib (Tagrisso) in patients over age 80 with advanced small cell lung cancer (NSCLC). This study found that these elderly patients had similar outcomes to patients in clinical trials. Some background NSCLC is the most common type of lung cancer. One common treatment is...
Read MoreIs bevacizumab a safe and effective treatment for advanced non-small cell lung cancer?
In a nutshell This study investigated the effectiveness of bevacizumab (Avastin) in combination with platinum-based chemotherapy in Hungarian patients with non-small-cell lung cancer (NSCLC). They found that this treatment combination was associated with improved patient survival. Some background The most common type of lung cancer is...
Read MoreIs the biosimilar drug ABP 125 as effective as bevacizumab in patients with lung cancer?
In a nutshell This study examined how safe and effective is biosimilar ABP 215 in non-small cell lung cancer (NSCLC), compared to bevacizumab (Avastin). This study concluded that this drug is as safe and effective as bevacizumab in these patients. Some background Non-small cell lung cancer (NSCLC) is the most common type of lung...
Read MoreRadiotherapy for patients with advanced non-small cell lung cancer
In a nutshell This study wanted to find out how well radiotherapy treatment works for people with stage 4 non-small cell lung cancer. The study found that overall survival was improved in patients who had radiotherapy treatment compared to those who did not. Some background There are a number of options for treatment of non-small cell lung...
Read MoreNab-paclitaxel plus cc-486 as treatment for non-small cell lung cancer
In a nutshell This study wanted to find which combination of medications worked best for advanced non-small cell lung cancer, nab-paclitaxel (Abraxane) alone, or nab-paclitaxel plus CC-486. The study found that there was no benefit seen when CC-486 was added to treatment with nab-paclitaxel. Some background There are a number of options for...
Read MoreCan vitamin D supplements prevent relapse in non-small-cell lung cancer?
In a nutshell This study looked at the effect of vitamin D supplements at preventing relapse in non-small-cell lung cancer (NSCLC). The authors concluded that vitamin D supplements might have the potential for improving survival in patients with early-stage lung adenocarcinoma. Some background Current therapy for early-stage NSCLC...
Read MoreCombining antiangiogenic drugs and chemotherapy to treat advanced NSCLC
In a nutshell This study looked at a combination of chemotherapy and an antiangiogenic drug bevacizumab to treat patients with advanced non-small-cell lung cancer. The authors concluded that this combination may have potential to control cancer in these patients. Some background Despite the major advances in cancer treatments in recent years,...
Read MoreCombining immunotherapy to current NSCLC cancer treatment regimes
In a nutshell This study looked at the benefit of adding the immunotherapy drug atezolizumab (Tecentriq) to bevacizumab (Avastin) and chemotherapy. The authors stated that combining atezolizumab to bevacizumab and chemotherapy treatment improved progression free survival and overall survival for patients with advanced non-small-cell lung cancer....
Read MoreTesting biological therapy in treating KRAS-mutant NSCLC
In a nutshell This study aimed to assess the efficacy and safety of anti-cancer drug trametinib (Mekinist) in comparison to docetaxel (Taxotere) in treating patients with KRAS-mutation-positive advanced non-small-cell lung cancer (NSCLC). The study concluded that there was no difference in efficacy between trametinib and docetaxel however trametinib...
Read MoreTreatments for when lung cancer progresses
In a nutshell This review discussed the use of nintedanib (Vargatef) in non-small cell lung cancer that has progressed despite treatment. Some background Non-small cell lung cancer (NSCLC) is often not diagnosed until the disease is advanced (spread to the lymph nodes or other areas of the body). Chemotherapy is the first-line treatment, but the...
Read MoreErlotinib with pemetrexed and cisplatin for lung cancer that has spread to the brain
In a nutshell The objective of this study was to evaluate the effect of erlotinib (Tarceva) in combination with pemetrexed (Alimta) and cisplatin (Platinol) in lung cancer that had spread into the brain (brain metastases). Some background Lung adenocarcinoma is the cancer of glandular cells of lungs. It is a common type of non-small cell lung...
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