In a nutshell This study aimed to investigate the outcomes of a second hematopoietic stem cell transplant (HSCT) after reduced-intensity conditioning (RIC) for patients with leukemia or lymphoma. This study concluded that this treatment path is feasible and a good alternative for these patients. Some background Allogenic hemopoietic...
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Impact of graft cryopreservation on allogeneic hematopoietic stem cell transplant outcomes using post-transplant cyclophosphamide
In a nutshell This study aimed to compare outcomes of allogeneic hematopoietic stem cell transplant (alloHSCT) using cryopreserved (frozen) and fresh grafts in patients with blood cancers who received post-transplant cyclophosphamide (Cytoxan). This study concluded that cryopreservation (CP) does...
Read MoreHow useful is preimplantation genetic testing for aneuploidy for fertility preservation in cancer patients?
In a nutshell This study investigated preimplantation genetic testing for aneuploidy (PGT-A) for fertility preservation (FP). They found that PGT-A was useful in cancer patients attempting FP. Some background Assisted reproductive technology (ART) is used to treat infertility. It is also an important option for cancer patients. Cancer...
Read MoreSearching for patients with different types of leukemia to test modified stem cell transplants donated by relatives
In a nutshell This trial is examining the effectiveness of modified stem cell transplants (SCT) donated by patient relatives, which have certain immune cells removed to prevent transplant rejection in patients with leukemia and lymphoma. The main outcome will be the maximum dose of SCT that can be given safely and is effective. This study is recruiting...
Read MoreExamining azacitidine-based treatment approaches
In a nutshell This study examined 3 different azacitidine-based (Vidaza) treatment approaches for patients with chronic myelomonocytic leukemia (CMML). Researchers reported that patients with CMML showed better treatment response when azacitidine was combined with lenalidomide (Revlimid). Some background Myelodysplastic syndromes (MDS) are a group...
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